[HTML][HTML] Mesenchymal stem cells as a potential therapeutic tool to cure cognitive impairment caused by neuroinflammation

M Skok - World Journal of Stem Cells, 2021 - ncbi.nlm.nih.gov
An established contribution of neuroinflammation to multiple brain pathologies has raised
the requirement for therapeutic strategies to overcome it in order to prevent age-and disease …

Acetylcholine receptors in mesenchymal stem cells

S Alqahtani, MC Butcher, G Ramage… - Stem Cells and …, 2023 - liebertpub.com
Mesenchymal stem cells (MSCs) are well known for their regenerative potential. Even
though the ability of MSCs to proliferate and differentiate has been studied extensively, there …

[HTML][HTML] Hydroxyurea interaction with α7 nicotinic acetylcholine receptor can underlie its therapeutic efficacy upon COVID-19

O Lykhmus, O Kalashnyk, R Sullivan Jr… - Journal of …, 2023 - Elsevier
In this paper the authors provide evidence that hydroxyurea (hydroxycarbamide) interacts
with α7 nicotinic acetylcholine receptor, exerts anti-inflammatory and pro-survival effect …

Mesenchymal stem cell application for treatment of neuroinflammation-induced cognitive impairment in mice

M Skok, O Deryabina, O Lykhmus… - Regenerative …, 2022 - Taylor & Francis
Background: The present research has been undertaken to study the therapeutic potential of
mesenchymal stem cells (MSCs) for the treatment of neuroinflammation-induced cognitive …

Positive allosteric modulation of alpha7 nicotinic acetylcholine receptors transiently improves memory but aggravates inflammation in LPS-treated mice

O Lykhmus, O Kalashnyk, K Uspenska… - Frontiers in Aging …, 2020 - frontiersin.org
Neuroinflammation accompanies or even precedes the development of cognitive changes in
many brain pathologies, including Alzheimer's disease. Therefore, dampening inflammatory …

[HTML][HTML] Universal nature of cholinergic regulation demonstrated with nicotinic acetylcholine receptors

M Skok - BBA advances, 2022 - Elsevier
Mammalian nicotinic acetylcholine receptors (nAChRs) were initially discovered as ligand-
gated ion channels mediating fast synaptic transmission in the neuro-muscular junctions …

[HTML][HTML] Inflammation at diagnosis and cognitive impairment two years later in breast cancer patients from the Canto-Cog study

M Duivon, J Lequesne, A Di Meglio… - Breast Cancer …, 2024 - ncbi.nlm.nih.gov
Background Inflammation could be related to cancer-related cognitive impairment (CRCI)
and might be used as a predictive marker of long-term CRCI. We evaluated associations …

Simultaneous Pericytes and M2 Microglia Transplantation Improve Cognitive Function in Mice Model of mPFC Ischemia

MH Geranmayeh, F Farokhi-Sisakht, S Sadigh-Eteghad… - Neuroscience, 2023 - Elsevier
Cerebral ischemia is one of the major problems threatening global health. Many of the
cerebral ischemia survivors would suffer from the physical and cognitive disabilities for their …

Different effects of nicotine and N-Stearoyl-ethanolamine on episodic memory and brain mitochondria of α7 nicotinic acetylcholine receptor knockout mice

O Lykhmus, O Kalashnyk, K Uspenska, T Horid'ko… - Biomolecules, 2020 - mdpi.com
Nicotinic acetylcholine receptors of α7 subtype (α7 nAChRs) are involved in regulating
neuroinflammation and cognitive functions. Correspondingly, α7-/-mice demonstrate pro …

Does stem cells approach ameliorate the prospective alterations of mandibular joint histology and acetylcholinesterase expression in experimentally induced …

F Saad, AM Abdellah - Egyptian Journal of Histology, 2021 - journals.ekb.eg
Background: Alzheimer's disease (AD) is a neurodegenerative disorder characterized by a
progressive degenerative brain disorder. This work aimed to illuminate the possible effects …