Malaria causes high levels of morbidity and mortality in human beings worldwide. According
to the World Health Organization (WHO), about half a million people die of this disease each …

Over the last century, a great deal of effort and resources have been poured into the
development of vaccines to protect against malaria, particularly targeting the most widely …

Malaria transmission and endemicity in Africa remains hugely disproportionate compared to
the rest of the world. The complex life cycle of P. falciparum (Pf) between the vertebrate …

Plasmodium falciparum and Toxoplasma gondii are obligate intracellular parasites that
belong to the phylum of Apicomplexa and cause major human diseases. Their access to an …

Plasmodium falciparum immune escape mechanisms affect antigens being prioritized for
vaccine design. As a result of the multiple surface antigens the parasite exhibits at different …

The ability to accurately measure the intensity of malaria transmission in areas with low
transmission is extremely important to guide elimination efforts. Plasmodium falciparum Cell …

The cell-traversal protein for ookinetes and sporozoites (CelTOS), expressed on the surface
of ookinetes and sporozoitesin Plasmodium species, is a promising malaria vaccine …

Malaria remains a global public health challenge. The disease has a great impact in sub-
Saharan Africa among children under five years of age and pregnant women. Malaria …

Sterile protection against clinical malaria has been achieved in animal models and
experimental human challenge studies involving immunization with radiation attenuated …

Currently, there is no subunit malaria vaccine capable of providing long-lasting protection,
and a vaccine based on a single-antigen has shown moderate to unsatisfactory efficacies in …