Juvenile idiopathic arthritis

A Martini, DJ Lovell, S Albani, HI Brunner… - Nature Reviews …, 2022 - nature.com
Juvenile idiopathic arthritis (JIA) is an umbrella term for arthritis of unknown origin, lasting
for> 6 weeks with onset before 16 years of age. JIA is the most common chronic …

Clinical outcome measures in juvenile idiopathic arthritis

A Consolaro, G Giancane, B Schiappapietra… - Pediatric …, 2016 - Springer
Juvenile idiopathic arthritis (JIA), as a chronic condition, is associated with significant
disease-and treatment-related morbidity, thus impacting children's quality of life. In order to …

2021 American College of Rheumatology guideline for the treatment of juvenile idiopathic arthritis: therapeutic approaches for oligoarthritis, temporomandibular joint …

KB Onel, DB Horton, DJ Lovell, S Shenoi… - Arthritis & …, 2022 - Wiley Online Library
Objective To provide updated guidelines for pharmacologic management of juvenile
idiopathic arthritis (JIA), focusing on treatment of oligoarthritis, temporomandibular joint …

Tofacitinib in juvenile idiopathic arthritis: a double-blind, placebo-controlled, withdrawal phase 3 randomised trial

N Ruperto, HI Brunner, O Synoverska, TV Ting… - The Lancet, 2021 - thelancet.com
Background Tofacitinib is an oral Janus kinase inhibitor. This trial assessed the efficacy and
safety of tofacitinib versus placebo in patients with polyarticular course juvenile idiopathic …

Treating juvenile idiopathic arthritis to target: recommendations of an international task force

A Ravelli, A Consolaro, G Horneff, RM Laxer… - Annals of the …, 2018 - ard.bmj.com
Recent therapeutic advances in juvenile idiopathic arthritis (JIA) have made remission an
achievable goal for most patients. Reaching this target leads to improved outcomes. The …

[HTML][HTML] Two randomized trials of canakinumab in systemic juvenile idiopathic arthritis

N Ruperto, HI Brunner, P Quartier… - … England Journal of …, 2012 - Mass Medical Soc
Background Interleukin-1 is pivotal in the pathogenesis of systemic juvenile idiopathic
arthritis (JIA). We assessed the efficacy and safety of canakinumab, a selective, fully human …

Baricitinib in juvenile idiopathic arthritis: an international, phase 3, randomised, double-blind, placebo-controlled, withdrawal, efficacy, and safety trial

AV Ramanan, P Quartier, N Okamoto, I Foeldvari… - The Lancet, 2023 - thelancet.com
Background Juvenile idiopathic arthritis can be refractory to some or all treatment regimens,
therefore new medications are needed to treat this population. This trial assessed the …

Long‐Term outcomes in juvenile idiopathic arthritis: eighteen years of Follow‐Up in the Population‐Based Nordic juvenile idiopathic arthritis cohort

M Glerup, V Rypdal, ED Arnstad… - Arthritis care & …, 2020 - Wiley Online Library
Objective The present study was undertaken to assess the long‐term course, remission rate,
and disease burden in juvenile idiopathic arthritis (JIA) 18 years after disease onset in a …

Emergent high fatality lung disease in systemic juvenile arthritis

VE Saper, G Chen, GH Deutsch… - Annals of the …, 2019 - ard.bmj.com
Objective To investigate the characteristics and risk factors of a novel parenchymal lung
disease (LD), increasingly detected in systemic juvenile idiopathic arthritis (sJIA). Methods In …

The outcomes of juvenile idiopathic arthritis in children managed with contemporary treatments: results from the ReACCh-Out cohort

J Guzman, K Oen, LB Tucker, AM Huber… - Annals of the …, 2015 - ard.bmj.com
Objective To describe clinical outcomes of juvenile idiopathic arthritis (JIA) in a prospective
inception cohort of children managed with contemporary treatments. Methods Children …