The mucus clearance system is the dominant mechanical host defense system of the human
lung. Mucus is cleared from the lung by cilia and airflow, including both two-phase gas-liquid …

Bronchiectasis — A Clinical Review | New England Journal of Medicine Skip to main content The
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Background Bronchiectasis is a heterogeneous, neglected disease with few multicentre
studies exploring the causes, severity, microbiology, and treatment of the disease across …

BACKGROUND: Increasing evidence suggests that post-TB lung disease (PTLD) causes
significant morbidity and mortality. The aim of these clinical standards is to provide guidance …

Bronchiectasis refers to both a clinical disease and a radiological appearance that has
multiple causes and can be associated with a range of conditions. Disease heterogeneity …

There is increasing awareness of bronchiectasis in children and adolescents, a chronic
pulmonary disorder associated with poor quality of life for the child/adolescent and their …

An estimated 58 million people have survived tuberculosis since 2000, yet many of them will
suffer from post-tuberculosis lung disease (PTLD). PTLD results from a complex interplay …

Bronchiectasis is characterised by pathological dilation of the airways. More specifically, the
radiographic demonstration of airway enlargement is the common feature of a …

Rationale: Bronchiectasis is classically considered a neutrophilic disorder, but eosinophilic
subtypes have recently been described. Objectives: To use multiple datasets available …

Background Bronchiectasis is predominantly a neutrophilic inflammatory disease. There are
no established therapies that directly target neutrophilic inflammation because little is …