In the past decade RNA-based therapies such as small interfering RNA (siRNA) and messenger RNA (mRNA) have emerged as new and ground-breaking therapeutic agents for …
Introduction Aerosol therapy is commonly prescribed in the mechanically ventilated patient. Jet nebulizers (JN) and vibrating mesh nebulizers (VMN) are the most common nebulizer …
PJ Naughton, M Joyce, M Mac Giolla Eain, A O'Sullivan… - Pharmaceutics, 2021 - mdpi.com
Drug delivery devices used for aerosol therapy during mechanical ventilation to ease the symptoms of respiratory diseases provide beneficial treatment but can also pose challenges …
A Arnott, M Watson, M Sim - Journal of The Intensive Care …, 2024 - journals.sagepub.com
Nebulisers are devices that reduce a body of liquid into a fine aerosol suitable for inhalation. Utilising the efficiency of pulmonary drug absorption, they offer a safe and powerful modality …
LC Brennan, A O'Sullivan, R MacLoughlin - International Journal of …, 2021 - mdpi.com
Respiratory disease is the leading cause of death in children under the age of 5 years old. Currently available treatments for paediatric respiratory diseases including …
E Fernandez Fernandez, M Joyce, A O'Sullivan… - Antibiotics, 2021 - mdpi.com
Lung disease is the main cause of morbidity and mortality in cystic fibrosis (CF). CF patients inhale antibiotics regularly as treatment against persistent bacterial infections. The goal of …
L Reilly, M Mac Giolla Eain, S Murphy… - Frontiers in …, 2024 - frontiersin.org
Introduction Aerosol therapy is often prescribed concurrently during invasive mechanical ventilation (IMV). This study determines the effects of nebuliser position, circuit …
B Murphy, MMG Eain, M Joyce, JB Fink… - ERJ open …, 2022 - Eur Respiratory Soc
Question addressed by study Administration of aerosol to patients receiving high-flow nasal oxygen (HFNO) ranges from concurrent aerosol delivery by mouthpiece to aerosol via …
LC Nagle, A Wahl, V Ogourstov, I Seymour, F Barry… - Sensors, 2021 - mdpi.com
The emergence of specific drug–device combination products in the inhalable pharmaceutical industry demands more sophistication of device functionality in the form of …