Papillomaviridae is a family of small non-enveloped icosahedral viruses with double-
stranded circular DNA. More than 200 different human papillomaviruses (HPVs) have been …

The study of antiviral pathways to reveal methods for the effective response and clearance of
virus is closely related to understanding interferon (IFN) signaling and its downstream target …

Background Most uterine cervical high-risk human papillomavirus (HPV) infections are
transient, with only a small fraction developing into cervical cancer. Family aggregation …

Objectives The objective of the present study is to assess the performance of a high-risk
human papillomavirus (HR-HPV) DNA test with individual HPV-16/HPV-18 genotyping as a …

Cancer is fueled by mutations and driven by adaptive selection. Normal cells avoid
deleterious mutations by replicating their genomes with extraordinary accuracy. Here we …

A small percentage of women with cervical HPV infection progress to cervical neoplasia,
and the risk factors determining progression are incompletely understood. We sought to …

Simple Summary Cervical cancer is the fourth leading cause of cancer-related deaths in
females worldwide. Despite an active immunisation strategy in many countries, high-risk …

Probiotics have been proposed for a number of urogenital infectious conditions. In this study,
we examine a possible effect on human papillomavirus (HPV)-related precancerous lesions …

Three DNA polymerases—Pol α, Pol δ and Pol ɛ—are essential for DNA replication. After
initiation of DNA synthesis by Pol α, Pol δ or Pol ɛ take over on the lagging and leading …

Cervical and other anogenital cancers are initiated by infection with one of a small group of
human papillomaviruses (HPV). Virus-like particle-based vaccines have recently been …