Targeting mammalian 5-lipoxygenase by dietary phenolics as an anti-inflammatory mechanism: A systematic review

JA Giménez-Bastida, A Gonzalez-Sarrias… - International Journal of …, 2021 - mdpi.com
5-Lipoxygenase (5-LOX) plays a key role in inflammation through the biosynthesis of
leukotrienes and other lipid mediators. Current evidence suggests that dietary (poly) …

In vitro and in vivo antimalarial activity and chemical profiling of sugarcane leaves

JE Okokon, R Mobley, UA Edem, AI Bassey… - Scientific Reports, 2022 - nature.com
Abstract Saccharum officinarum Linn.(sugarcane, Family-Poaceae) is employed in Ibibio
traditional medicine for the treatment of various infections and diseases such as malaria. We …

[HTML][HTML] Mechanistic Insights into the Anticancer Potential of Methoxyflavones Analogs: A Review

M Aidiel, M Abdul Mutalib, R Ramasamy, NN Nik Ramli… - Molecules, 2025 - mdpi.com
2-phenylchromen-4-one, commonly known as flavone, plays multifaceted roles in biological
response that can be abundantly present in natural sources. The methoxy group in naturally …

Oriental Hornet (Vespa orientalis) Larval Extracts Induce Antiproliferative, Antioxidant, Anti-Inflammatory, and Anti-Migratory Effects on MCF7 Cells

AMG Zedan, MI Sakran, O Bahattab, YM Hawsawi… - Molecules, 2021 - mdpi.com
The use of insects as a feasible and useful natural product resource is a novel and
promising option in alternative medicine. Several components from insects and their larvae …

Potential antibacterial pharmaceuticals from the flora of Africa

AT Mbaveng, LK Omosa, GTM Bitchagno… - Advances in Botanical …, 2023 - Elsevier
The present chapter highlights the antibacterial potential of nine highly active compounds
isolated from the African medicinal plants: 8, 8-bis-(dihydroconiferyl)-diferulate, buesgenine …

Inhibition of Cysteine Proteases via Thiol-Michael Addition Explains the Anti-SARS-CoV-2 and Bioactive Properties of Arteannuin B

K Varela, HD Arman, MS Berger… - Journal of Natural …, 2023 - ACS Publications
Artemisia annua is the plant that produces artemisinin, an endoperoxide-containing
sesquiterpenoid used for the treatment of malaria. A. annua extracts, which contain other …

Phenolic Compounds and Antioxidant Activity of Chiliadenus montanus (Vhal.) Brullo. grown in vitro

D Abu-Darwish, R Shibli… - Jordan Journal of …, 2024 - jjournals.ju.edu.jo
This study explores the in vitro cultivation of Chiliadenus montanus (Vhal.) Brullo
(Asteraceae), focusing on callus multiplication, in vitro seed germination, phenolic …

Geiparvarin Inhibits the Progression of Osteosarcoma by Down-regulating COX2 Expression

B Wang, J Du, Z Zhang, P Huang… - Current Cancer Drug …, 2023 - ingentaconnect.com
Background: Geiparvarin (GN) is a natural compound isolated from the leaves of Geijera
parviflora and exhibits anticancer activity. Nevertheless, little is known about its anticancer …

Phytoconstituents from Adenanthera pavonina L. as antioxidants and inhibitors of inducible TNF-α production in BV2 cells

SM Mohamed, EHM Hassanein, SA Ross… - Natural Product …, 2022 - Taylor & Francis
Adenanthera pavonina L. has been used traditionally to relieve inflammation. This study
aimed to expand the phytochemical knowledge of A. pavonina and evaluate its constituents …

Polyphenols of the Inuleae-Inulinae and Their Biological Activities: A Review

J Malarz, K Michalska, A Stojakowska - Molecules, 2024 - mdpi.com
Polyphenols are ubiquitous plant metabolites that demonstrate biological activities essential
to plant–environment interactions. They are of interest to plant food consumers, as well as to …