Synthetic routes to quinoline-based derivatives having potential anti-bacterial and anti-fungal properties
S Sharma, S Singh - Current Organic Chemistry, 2022 - benthamdirect.com
Quinoline and its derivatives are part of several natural products. Many of them are active
pharmacophores and show enormous biological activities. Owing to their usefulness in drug …
pharmacophores and show enormous biological activities. Owing to their usefulness in drug …
[HTML][HTML] Investigating the potential of thiazolyl carbohydrazides derivatives as anti-Candida albicans agents: an intuition from molecular modelling, pharmacokinetic …
I Benjamin, CU Benson, SA Adalikwu, FA Nduoma… - Chemical Physics …, 2023 - Elsevier
With increasing incidences of antifungal resistance, biofilm formation, and its predilection for
vulnerable populations, Candida albicans have been reported to cause a wide range of …
vulnerable populations, Candida albicans have been reported to cause a wide range of …
In Silico Computational Studies of Bioactive Secondary Metabolites from Wedelia trilobata against Anti-Apoptotic B-Cell Lymphoma-2 (Bcl-2) Protein Associated with …
HG Gowtham, F Ahmed, S Anandan, CS Shivakumara… - Molecules, 2023 - mdpi.com
In the present study, the binding affinity of 52 bioactive secondary metabolites from Wedelia
trilobata towards the anti-apoptotic B-cell lymphoma-2 (Bcl-2) protein (PDB: 2W3L) structure …
trilobata towards the anti-apoptotic B-cell lymphoma-2 (Bcl-2) protein (PDB: 2W3L) structure …
Synthesis, computational pharmacokinetics report, conceptual DFT-based calculations and anti-acetylcholinesterase activity of hydroxyapatite nanoparticles derived …
Over the years, Alzheimer's disease (AD) treatments have been a major focus, culminating
in the identification of promising therapeutic targets. A herbal therapy approach has been …
in the identification of promising therapeutic targets. A herbal therapy approach has been …
Molecular insights into the in silico discovery of corilagin from Terminalia chebula as a potential dual inhibitor of SARS-CoV-2 structural proteins
The spike (S) glycoprotein and nucleocapsid (N) proteins are the crucial pathogenic proteins
of the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS CoV-2) virus during its …
of the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS CoV-2) virus during its …
Anticholinesterase activity of Areca Catechu: In Vitro and in silico green synthesis approach in search for therapeutic agents against Alzheimer's disease
S Pradeep, SC Prabhuswaminath, P Reddy… - Frontiers in …, 2022 - frontiersin.org
For many years, the primary focus has been on finding effective treatments for Alzheimer's
disease (AD), which has led to the identification of promising therapeutic targets. The …
disease (AD), which has led to the identification of promising therapeutic targets. The …
Tandem-Michael-cyclization cascade to make pyridines: Use of electron-deficient acetylenes for the synthesis of indolizines in aqueous media
K Lakshmikanth, SM Saini, ST Dorai… - Tetrahedron, 2023 - Elsevier
A mild, greener approach via tandem-Michael-cyclization cascade reaction towards the
construction of a group of di-and tri-differently substituted indolizine with a broad scope of …
construction of a group of di-and tri-differently substituted indolizine with a broad scope of …
Synthesis of novel pyrrolo [1, 2-a] quinoline derivatives as a new class of anti-inflammatory and antimicrobial agents: An approach to single crystal X-ray structure …
We report the synthesis and characterisation of pyrrolo [1, 2-a] quinoline derivatives 3a-c.
The synthesised compounds were characterised by FTIR, 1 H NMR, 13 C NMR, and mass …
The synthesised compounds were characterised by FTIR, 1 H NMR, 13 C NMR, and mass …
One-pot construction of novel trifluoromethyl dihydro-imidazo [1, 2-a] pyridine: A greener approach
A one-pot three-component method for the synthesis of 3-substituted 2-trifluoromethyl-2, 3-
dihydroimidazo [1, 2-a] pyridin-3-yl analogues from 2-aminopyridine, substituted phenacyl …
dihydroimidazo [1, 2-a] pyridin-3-yl analogues from 2-aminopyridine, substituted phenacyl …
Design, synthesis and in vitro antitubercular evaluation of novel 7-methoxy pyrrolo [1, 2-a] quinoline analogues as CYP 121 inhibitors
K Shivaprasad, S Kidwai, S Gopavaram… - Journal of Molecular …, 2023 - Elsevier
A novel series of pyrrolo [1, 2-a] quinoline analogues (4a-n) was designed via a heterocyclic
fusion approach for their antitubercular evaluation. The targeted compounds were …
fusion approach for their antitubercular evaluation. The targeted compounds were …