Stimuli-responsive nano-architecture drug-delivery systems to solid tumor micromilieu: past, present, and future perspectives

HS El-Sawy, AM Al-Abd, TA Ahmed, KM El-Say… - ACS …, 2018 - ACS Publications
The microenvironment characteristics of solid tumors, renowned as barriers that harshly
impeded many drug-delivery approaches, were precisely studied, investigated, categorized …

[HTML][HTML] The smart drug delivery system and its clinical potential

D Liu, F Yang, F Xiong, N Gu - Theranostics, 2016 - ncbi.nlm.nih.gov
With the unprecedented progresses of biomedical nanotechnology during the past few
decades, conventional drug delivery systems (DDSs) have been involved into smart DDSs …

pH-sensitive ZnO/carboxymethyl cellulose/chitosan bio-nanocomposite beads for colon-specific release of 5-fluorouracil

X Sun, C Liu, AM Omer, W Lu, S Zhang, X Jiang… - International journal of …, 2019 - Elsevier
To develop relatively green and ecofriendly smart vehicles for colon-specific drug delivery,
carboxymethyl cellulose (CMC) and chitosan (CS) pH-sensitive biopolymers were used in …

Chondroitin sulphate: a focus on osteoarthritis

M Bishnoi, A Jain, P Hurkat, SK Jain - Glycoconjugate journal, 2016 - Springer
Chondroitin sulfate (CS) being a natural glycosaminoglycan is found in the cartilage and
extracellular matrix. It shows clinical benefits in symptomatic osteoarthritis (OA) of the finger …

[HTML][HTML] Chitosan-tripolyphosphate nanoparticles designed to encapsulate polyphenolic compounds for biomedical and pharmaceutical applications− A review

MC Di Santo, CL D'Antoni, APD Rubio, A Alaimo… - Biomedicine & …, 2021 - Elsevier
Plant-based polyphenols are natural compounds, present in fruits and vegetables. During
recent years, polyphenols have gained special attention due to their nutraceutical and …

Alginate as promising natural polymer for pharmaceutical, food, and biomedical applications

D Kothale, U Verma, N Dewangan, P Jana… - Current drug …, 2020 - ingentaconnect.com
Alginates are biopolymers usually obtained from brown seaweed, brown algae (Ochrophyta,
Phaeophyceae), and bacteria (Azatobacter vineland and Pseudomonas species) belonging …

A Systematic Overview of Eudragit® Based Copolymer for Smart Healthcare

A Nikam, PR Sahoo, S Musale, RR Pagar… - Pharmaceutics, 2023 - mdpi.com
Eudragit, synthesized by radical polymerization, is used for enteric coating, precise temporal
release, and targeting the entire gastrointestinal system. Evonik Healthcare Germany offers …

Synthesis of 5-fluorouracil cocrystals with novel organic acids as coformers and anticancer evaluation against HCT-116 colorectal cell lines

F Jubeen, A Liaqat, F Amjad, M Sultan… - Crystal Growth & …, 2020 - ACS Publications
5-Fluorouracil (5-FU) being a mainstream anticancer drug is under keen and detailed
investigation for prodrugs formulations in order to minimize the associated side effects …

[HTML][HTML] Polymeric nanocarriers: A promising tool for early diagnosis and efficient treatment of colorectal cancer

M Haider, KZ Zaki, MR El Hamshary, Z Hussain… - Journal of advanced …, 2022 - Elsevier
Background Colorectal cancer (CRC) is the third most prevalent type of cancer for incidence
and second for mortality worldwide. Late diagnosis and inconvenient and expensive current …

Stimuli-sensitive drug delivery systems for site-specific antibiotic release

F Nazir, TA Tabish, F Tariq, S Iftikhar, R Wasim… - Drug Discovery …, 2022 - Elsevier
Site-specific delivery of antibiotics has always been a high-priority area in pharmaceutical
research. Conventionally used antibiotics suffer several limitations, such as low …