The Hippo signaling pathway, also known as the Salvador− Warts− Hippo pathway, is a
regulator of organ size. The pathway takes its name from the Drosophila protein kinase …

YAP1 is a transcriptional co-activator whose activity is controlled by the Hippo signaling
pathway. In addition to important functions in normal tissue homeostasis and regeneration …

Abstract Background Non-coding RNAs (ncRNAs) have been shown to regulate gene
expression involved in tumor progression of multiple malignancies. Our previous studies …

Proper cellular functionality and homeostasis are maintained by the convergent integration
of various signaling cascades, which enable cells to respond to internal and external …

Emerging studies indicate that the Hippo pathway, a highly conserved pathway that
regulates organ size control, plays an important role in governing ovarian physiology …

Background With persistent inconsistencies in colorectal cancer (CRC) miRNAs expression
data, it is crucial to shift toward inclusion of a “pre-laboratory” integrated analysis to expedite …

The Human Genome Project led to the discovery that about 80% of our DNA is transcribed in
RNA molecules. Only 2% of the human genome is translated into proteins, the rest mostly …

Endometrial cancer is the most common gynecologic malignancy, whose incidence rate is
on the rise. However, the underlying mechanisms of endometrial cancer are not very clear …

The liver is the only visceral organ in the body with a tremendous capacity to regenerate in
response to insults that induce inflammation, cell death, and injury. Liver regeneration is a …

Gynecological cancers (GCs) are often diagnosed at advanced stages, limiting the efficacy
of available therapeutic options. Thus, there remains an urgent and unmet need for …