Wound healing studies are intricate, mainly because of the multifaceted nature of the wound
environment and the complexity of the healing process, which integrates a variety of cells …

Type II diabetes mellitus (T2DM) is one of the most prevalent diseases in the world,
associated with diabetic foot ulcers and impaired wound healing. There is an ongoing need …

Wound healing capability is inextricably linked with diverse aspects of physical fitness
ranging from recovery after minor injuries and surgery to diabetes and some types of cancer …

Nanofibrous membranes produced by electrospinning possess a large surface area-to-
volume ratio, which mimics the three-dimensional structure of the extracellular matrix. Thus …

Diabetic foot ulcers (DFUs) are a significant health problem. A single existing FDA-approved
drug for this ailment, becaplermin, is not standard-of-care. We previously demonstrated that …

Current understanding of the complex process of wound repair is based on decades of
study. Integral to this understanding has been the use of in vitro and in vivo models to …

Nitric oxide (NO) is an unstable signalling molecule synthesized de novo mainly from l-
arginine by NO synthase (NOS) enzymes. Nitrite reduction can also produce NO …

The LL37 is a human antimicrobial peptide which not only has a broad spectrum of
antimicrobial activity, but it has also been proved to modulate wound healing by participating …

Electrospun nanofibrous dressings present suitable characteristics to be used in wound
healing, such as high porosity and high surface area-to-volume ratio. In this study, a wound …

Mice represent the most commonly used species for preclinical in vivo research. While
incisional and excisional acute murine wound models are both frequently employed, there is …