Liquid biopsies: the future of cancer early detection

S Connal, JM Cameron, A Sala, PM Brennan… - Journal of translational …, 2023 - Springer
Cancer is a worldwide pandemic. The burden it imposes grows steadily on a global scale
causing emotional, physical, and financial strains on individuals, families, and health care …

Circulating cells with macrophage-like characteristics in cancer: the importance of circulating neoplastic-immune hybrid cells in cancer

TL Sutton, RK Patel, AN Anderson, SG Bowden… - Cancers, 2022 - mdpi.com
Simple Summary In cancer, disseminated neoplastic cells circulating in blood are a source
of tumor DNA, RNA, and protein, which can be harnessed to diagnose, monitor, and better …

Liquid biopsy in glioblastoma

L Ronvaux, M Riva, A Coosemans, M Herzog… - Cancers, 2022 - mdpi.com
Simple Summary Glioblastoma is the most common and malignant primary brain tumor.
Despite intensive research for new treatments, the survival of patients has not significantly …

Liquid biopsy to detect minimal residual disease: methodology and impact

N Honoré, R Galot, C van Marcke, N Limaye… - Cancers, 2021 - mdpi.com
Simple Summary The field of liquid biopsy is rapidly evolving. Techniques that improve
accuracy are constantly being developed, and clinicians increasingly use liquid biopsy as a …

Saliva‐based cell‐free DNA and cell‐free mitochondrial DNA in head and neck cancers have promising screening and early detection role

L Sayal, O Hamadah, A Almasri… - Journal of Oral …, 2023 - Wiley Online Library
Abstract Background Cell‐free DNA (cfDNA) and cell‐free mitochondrial DNA (cf‐mtDNA)
have been postulated as potential diagnostic and prognostic biomarkers for different human …

Liquid biopsy in colorectal cancer

S Najafi, J Majidpoor, K Mortezaee - Clinica Chimica Acta, 2024 - Elsevier
Liquid biopsy refers to a set of pathological samples retrieved from non-solid sources, such
as blood, cerebrospinal fluid, urine, and saliva through non-invasive or minimally invasive …

Circulating liquid biopsy biomarkers in Glioblastoma: advances and challenges

AA Seyhan - International Journal of Molecular Sciences, 2024 - pmc.ncbi.nlm.nih.gov
Gliomas, particularly glioblastoma (GBM), represent the most prevalent and aggressive
tumors of the central nervous system (CNS). Despite recent treatment advancements, patient …

Current and new frontiers in hereditary cancer surveillance: Opportunities for liquid biopsy

KM Farncombe, D Wong, ML Norman… - The American Journal of …, 2023 - cell.com
At least 5% of cancer diagnoses are attributed to a causal pathogenic or likely pathogenic
germline genetic variant (hereditary cancer syndrome—HCS). These individuals are …

Genomic profiling of post-transplant lymphoproliferative disorders using cell-free DNA

N Veltmaat, Y Zhong, FM de Jesus, GW Tan… - Journal of Hematology & …, 2023 - Springer
Diagnosing post-transplant lymphoproliferative disorder (PTLD) is challenging and often
requires invasive procedures. Analyses of cell-free DNA (cfDNA) isolated from plasma is …

Comprehensive approach to distinguish patients with solid tumors from healthy controls by combining androgen receptor mutation p. H875Y with cell-free DNA …

E Tomeva, OJ Switzeny, C Heitzinger, B Hippe… - Cancers, 2022 - mdpi.com
Simple Summary Blood-based tests for cancer detection are minimally invasive and could
be useful for screening asymptomatic patients and high-risk populations. Since a single …