Diabetes and obesity: the role of stress in the development of cancer

A Avogaro - Endocrine, 2024 - Springer
Diabesity is a condition where an individual has both diabetes and obesity, which can lead
to severe complications including cardiovascular disease, a leading cause of mortality …

Tumorigenesis in inflammatory bowel disease: microbiota-environment interconnections

I Mignini, ME Ainora, S Di Francesco, L Galasso… - Cancers, 2023 - mdpi.com
Simple Summary The role of gut microbiota and environmental factors on IBD-related CRC
is still a burning question. Crohn's Disease (CD) and Ulcerative Colitis (UC) are complex …

The hallmarks of precancer

MM Stangis, Z Chen, J Min, SE Glass, JO Jackson… - Cancer discovery, 2024 - AACR
Research on precancers, as defined as at-risk tissues and early lesions, is of high
significance given the effectiveness of early intervention. We discuss the need for risk …

Snapshot into the type-2-diabetes-associated microbiome of a Romanian cohort

G Gradisteanu Pircalabioru, MC Chifiriuc… - International Journal of …, 2022 - mdpi.com
The prevalence of type 2 diabetes mellitus (T2D) is alarmingly increasing worldwide,
urgently calling for a better understanding of the underlying mechanisms in order to step up …

Association between diabetes and cancer. Current mechanistic insights into the association and future challenges

A Rojas, I Schneider, C Lindner, I Gonzalez… - Molecular and Cellular …, 2023 - Springer
Compelling pieces of epidemiological, clinical, and experimental research have
demonstrated that Diabetes mellitus (DM) is a major risk factor associated with increased …

Nutritional Profile, Disease Severity, and Quality of Life of Patients with Inflammatory Bowel Disease: A Case–Control Study

LN Sayegh, F Haddad, L Bou Jaoude… - Nutrients, 2024 - mdpi.com
Introduction: Diet is thought to play an important role in the clinical course and quality of life
(QOL) of patients with inflammatory bowel disease (IBD). However, dietary habits of patients …

[HTML][HTML] Uncovering the Therapeutic Potential of Lithium Chloride in Type 2 Diabetic Cardiomyopathy: Targeting Tau Hyperphosphorylation and TGF-β Signaling via …

L Abou Assi, S Alkhansa, R Njeim, J Ismail, M Madi… - Pharmaceutics, 2024 - mdpi.com
Diabetic cardiomyopathy (DCM) is a major complication of type 2 diabetes mellitus (T2DM)
that leads to significant morbidity and mortality. The alteration in the signaling mechanism in …

Moderate-intensity continuous training and high-intensity interval training alleviate glycolipid metabolism through modulation of gut microbiota and their metabolite …

Y Han, H Quan, W Ji, Q Tian, X Liu, W Liu - Biochemical and Biophysical …, 2024 - Elsevier
Glucose and lipid metabolism disorders are typical of diabetic patients and are important
factors leading to macrovascular and microvascular complications. The aim of this study was …

[PDF][PDF] Mitochondrial-epigenetic crosstalk as an integrative standpoint into gut microbiome dysbiosis and related diseases

VA SIMãO, LGDEA CHUFFA, LEN FERDER… - Biocell, 2024 - researchgate.net
The interplay between mitochondria, epigenetics, and the microbiota is intricately linked to
both health and disease. Within our cells, a complex molecular dance occurs, where these …

[PDF][PDF] Exploring the Molecular Biological Mechanisms of Type 2 Diabetes Mellitus Based on Intestinal Flora Metabolites that Affect Host-Associated Signaling …

L Lianchun, Q Yulong, L Qin - Frontiers in Medical Science …, 2024 - francis-press.com
Alterations in gut flora composition and function of the host have become a crucial area in
the pathogenesis of type 2 diabetes. This paper aims to discuss the molecular biological …