Oral squamous carcinogenesis is a multistep process in which multiple genetic events occur
that alter the normal functions of oncogenes and tumour suppressor genes. This can result …

Identification and management of potentially premalignant oral epithelial lesions (PPOELs)
at highest risk of malignant transformation holds great promise for successful secondary …

The clinical and histologic features alone cannot accurately predict whether potentially
malignant disorders of the oral mucosa remain stable, regress or progress to malignancy …

Since the first detection of aberrant crypt foci (ACF) in carcinogen-treated mice, there have
been numerous studies focusing on these microscopically visible lesions both in rodents …

The aim of this study was to define whether or not the impaired expression of CD44, E‐
cadherin (E‐cad), and β‐catenin (β‐cat) correlates with the clinical evolution and prognosis …

Plakophilins (PKPs) are members of the armadillo multigene family. Armadillo-related
proteins function in both cell adhesion and signal transduction, and also play a central role …

Background: Deranged expression and function of the E‐cadherin/β‐catenin (E‐cad/β‐cat)
complex and the epidermal growth factor receptor (EGFR) have been implicated in the …

Background Numerous attempts have been made to establish and develop tumor markers
that could determine the susceptibility of normal tissues to transform into cancerous ones. To …

Cell adhesion molecules (CAMs) are found on the surfaces of all cells, where they bind to
extracellular matrix molecules or to receptors on other cells. As well as having a structural …

Simple Summary β-catenin is a multifunctional protein whose physiological functions are
mainly related to the maintenance of cell-cell adhesion by forming complexes with the …