The 5th edition of this indispensable resource captures the latest insights in neonatal
neurology in a totally engaging, readable manner. World authority Dr. Joseph Volpe has …

The use of opioid analgesics has a long history in clinical settings, although the
comprehensive action of opioid receptors is still less understood. Nonetheless, recent …

Opioid overdose is the leading cause of death for Americans 25 to 64 years of age, and
opioid use disorder affects> 2 million Americans. The epidemiology of opioid-associated out …

To what extent are human beings capable of changing their physical characteristics and
behavioural patterns over the course of their lives? This question has engaged scientists for …

Increasing evidence has suggested that inflammation in the brain is closely associated with
the pathogenesis of several degenerative neurologic disorders, including Parkinson's …

Degeneration of dopaminergicrgic neurons in the substantia nigra of the brain is a hallmark
of Parkinson's disease and inflammation and oxidative stress are closely associated with the …

Opiates are among the oldest pharmacological substances known to man; their analgesic,
euphoric, and addictive effects have been traditional focal points for opiate research. Without …

A massive degeneration of dopamine-containing neurons in the substantia nigra (SN) in the
midbrain is characteristic of Parkinson's disease. Inflammation in the brain has long been …

Naloxone hydrochloride, a synthetic N-allyl derivative of oxymorphone, is an effective agent
for the reversal of the cardiovascular and respiratory depression associated with narcotic …

Whether naloxone may modulate energy metabolism and endogenous antioxidant enzyme
activities in ischemic cortex was studied. Cerebral ischemia/reperfusion (I/R) was produced …