Platelets are the primary cellular mediators of hemostasis and this function firmly acquaints
them with a variety of inflammatory processes. For example, platelets can act as circulating …

Monocytes (Mo) and macrophages (Mϕ) are key components of the innate immune system
and are involved in regulation of the initiation, development, and resolution of many …

Extracellular vesicles are heterogeneous populations of naturally occurring secreted small
vesicles. EVs function as signaling platforms to facilitate intracellular communication, which …

Systemic lupus erythematosus (SLE) is a chronic systemic autoimmune disease
characterized by dysregulated immune responses leading to widespread inflammation and …

Exosomes, nanometer-sized lipid-bilayer-enclosed extracellular vesicles (EVs), have
attracted increasing attention due to their inherent ability to shuttle proteins, lipids and genes …

Extracellular vesicles (EVs) are small membrane‐bound vesicles released by cells under
various conditions. They are found in the extracellular milieu in all biological fluids. As the …

Platelets play a major role in primary hemostasis and thrombus formation. After vascular
injury, platelets adhere to injured site and rapidly change their shape that switches the …

Lupus nephritis (LN) is a major cause for overall morbidity and mortality in patients with
systemic lupus erythematosus (SLE), while its pathogenic mechanisms are still not well …

Extracellular vesicles (EVs), naturally secreted by almost all known cell types into
extracellular space, can transfer their bioactive cargos of nucleic acids and proteins to …

Platelet-derived extracellular vesicles (PEVs) play important roles in hemostasis and
thrombosis. There are three major types of PEVs described based on their size and …