Small‐Molecule Quenchers for Förster Resonance Energy Transfer: Structure, Mechanism, and Applications

B Fang, Y Shen, B Peng, H Bai, L Wang… - Angewandte …, 2022 - Wiley Online Library
For fluorogenic probes, Förster resonance energy transfer (FRET) is one of the most widely
used mechanisms to realize the detection of biochemical activities. Dark quenchers relax …

Synthetic antigen-conjugated dna systems for antibody detection and characterization

S Ranallo, S Bracaglia, D Sorrentino, F Ricci - ACS sensors, 2023 - ACS Publications
Antibodies are among the most relevant biomolecular targets for diagnostic and clinical
applications. In this Perspective, we provide a critical overview of recent research efforts …

Gene-encoding DNA origami for mammalian cell expression

JA Kretzmann, A Liedl, A Monferrer… - Nature …, 2023 - nature.com
DNA origami may enable more versatile gene delivery applications through its ability to
create custom nanoscale objects with specific targeting, cell-invading, and intracellular …

DNA origami curvature sensors for nanoparticle and vesicle size determination with single-molecule FRET readout

E Büber, T Schröder, M Scheckenbach, M Dass… - ACS …, 2023 - ACS Publications
Particle size is an important characteristic of materials with a direct effect on their
physicochemical features. Besides nanoparticles, particle size and surface curvature are …

DNA Tile Self‐Assembly Guided by Base Excision Repair Enzymes

N Farag, G Ercolani, E Del Grosso… - Angewandte Chemie, 2022 - Wiley Online Library
We demonstrate here the use of DNA repair enzymes to control the assembly of DNA‐based
structures. To do so, we employed uracil‐DNA glycosylase (UDG) and formamidopyrimidine …

Lab-on-a-DNA origami: nanoengineered single-molecule platforms

S Kogikoski, J Ameixa, A Mostafa, I Bald - Chemical Communications, 2023 - pubs.rsc.org
DNA origami nanostructures are self-assembled into almost arbitrary two-and three-
dimensional shapes from a long, single-stranded viral scaffold strand and a set of short …

Single-Molecule FRET at 10 MHz Count Rates

L Grabenhorst, F Sturzenegger, M Hasler… - Journal of the …, 2024 - ACS Publications
A bottleneck in many studies utilizing single-molecule Förster resonance energy transfer is
the attainable photon count rate, as it determines the temporal resolution of the experiment …

Dynamic and Reversible Decoration of DNA‐Based Scaffolds

N Farag, M Đorđević, E Del Grosso… - Advanced Materials, 2023 - Wiley Online Library
An approach to achieving dynamic and reversible decoration of DNA‐based scaffolds is
demonstrated here. To do this, rationally engineered DNA tiles containing enzyme …

Maximizing the accessibility in DNA origami nanoantenna plasmonic hotspots

C Close, K Trofymchuk, L Grabenhorst… - Advanced Materials …, 2022 - Wiley Online Library
DNA nanotechnology has conquered the challenge of positioning quantum emitters in the
hotspot of optical antenna structures for fluorescence enhancement. Therefore, DNA origami …

Optical characterization of DNA origami-shaped silver nanoparticles created through biotemplated lithography

KM Kabusure, P Piskunen, J Yang, M Kataja… - Nanoscale, 2022 - pubs.rsc.org
Here, we study optically resonant substrates fabricated using the previously reported BLIN
(biotemplated lithography of inorganic nanostructures) technique with single triangle and …