Electron microscopy studies of soft nanomaterials

Z Lyu, L Yao, W Chen, FC Kalutantirige… - Chemical …, 2023 - ACS Publications
This review highlights recent efforts on applying electron microscopy (EM) to soft (including
biological) nanomaterials. We will show how developments of both the hardware and …

Opportunities and challenges in liquid cell electron microscopy

FM Ross - Science, 2015 - science.org
BACKGROUND Transmission electron microscopy offers structural and compositional
information with atomic resolution, but its use is restricted to thin, solid samples. Liquid …

Liquid‐phase electron microscopy for soft matter science and biology

H Wu, H Friedrich, JP Patterson… - Advanced …, 2020 - Wiley Online Library
Innovations in liquid‐phase electron microscopy (LP‐EM) have made it possible to perform
experiments at the optimized conditions needed to examine soft matter. The main obstacle is …

Liquid-EM goes viral–visualizing structure and dynamics

DF Kelly, LA DiCecco, GM Jonaid… - Current Opinion in …, 2022 - Elsevier
Abstract Liquid-electron microscopy (EM), the room temperature correlate to cryo-EM, is an
exciting new technique delivering real-time data of dynamic reactions in solution. Here, we …

Real-time visualization of nanoparticles interacting with glioblastoma stem cells

ES Pohlmann, K Patel, S Guo, MJ Dukes, Z Sheng… - Nano …, 2015 - ACS Publications
Nanoparticle-based therapy represents a novel and promising approach to treat
glioblastoma, the most common and lethal malignant brain cancer. Although similar …

Visualizing virus particle mobility in liquid at the nanoscale

AC Varano, A Rahimi, MJ Dukes, S Poelzing… - Chemical …, 2015 - pubs.rsc.org
Currently, there remains a critical need to develop real-time imaging resources for life
sciences. Here, we demonstrate the use of high resolution in situ imaging to observe …

Through a window, brightly: a review of selected nanofabricated thin-film platforms for spectroscopy, imaging, and detection

JR Dwyer, M Harb - Applied spectroscopy, 2017 - journals.sagepub.com
We present a review of the use of selected nanofabricated thin films to deliver a host of
capabilities and insights spanning bioanalytical and biophysical chemistry, materials …

Real-time observation of protein aggregates in pharmaceutical formulations using liquid cell electron microscopy

LM DiMemmo, AC Varano, J Haulenbeek, Y Liang… - Lab on a Chip, 2017 - pubs.rsc.org
Understanding the properties of protein-based therapeutics is a common goal of biologists
and physicians. Technical barriers in the direct observation of small proteins or therapeutic …

Liquid phase electron microscopy of biological specimens

DB Peckys, E Macías-Sánchez, N de Jonge - MRS Bulletin, 2020 - cambridge.org
Liquid phase electron microscopy is a new analytical method that has opened up a rapidly
emerging field of research during the past decade. This article discusses this new …

Carbon nanomaterials for biomedical application

SH Lee, WY Rho, H Chang, JH Lee, J Kim… - Nanotechnology for …, 2021 - Springer
The use of carbon-based nanomaterials (CNs) with outstanding properties has been rising
in many scientific and industrial application fields. These CNs represent a tunable …