Acute respiratory distress syndrome (ARDS) is characterized by acute diffuse lung injury,
which results in increased pulmonary vascular permeability and loss of aerated lung tissue …

Acute respiratory distress syndrome (ARDS) has been associated with secondary acute
brain injury (ABI). However, there is sparse literature on the mechanism of lung-mediated …

BACKGROUND: Intermittent hypoxia may occur in a number of clinical scenarios, including
interruption of myocardial blood flow or breathing disorders such as obstructive sleep …

The pulmonary endothelium is an immediate recipient of high oxygen concentrations upon
oxygen therapy and mediates down‐stream responses. Cyclic collapse and reopening of …

BACKGROUND Perioperative oxygen (O 2) therapy can cause hyperoxia. Extreme
hyperoxia can injure the cardiovascular system and remote organs. OBJECTIVE Our primary …

Background There is considerable interest in oxygen partial pressure (P o2) monitoring in
physiology, and in tracking P o2 changes dynamically when it varies rapidly. For example …

The lung can experience different oxygen concentrations, low as in hypoxia, high as under
supplemental oxygen therapy, or oscillating during intermittent hypoxia as in obstructive …

Background Perioperative high‐dose oxygen (O2) exposure can cause hyperoxia. While the
effect of constant hyperoxia on the vascular endothelium has been investigated to some …

Objective: Systemic PaO 2 oscillations occur during cyclic recruitment and derecruitment of
atelectasis in acute respiratory failure and might harm brain tissue integrity. Design …

Background Oscillations of the arterial partial pressure of oxygen induced by varying shunt
fractions occur during cyclic alveolar recruitment within the injured lung. Recently, these …