Immunotherapy: cancer immunotherapy and its combination with nanomaterials and other therapies

Y Guo, F Gao, A Ahmed, M Rafiq, B Yu… - Journal of Materials …, 2023 - pubs.rsc.org
Immunotherapy is a new type of tumor treatment after surgery, radiotherapy and
chemotherapy, which can be used to manage and destroy tumor cells through activating or …

Heme catabolism and heme oxygenase-1-expressing myeloid cells in pathophysiology

FM Consonni, M Incerti, M Bertolotti, G Ballerini… - Frontiers in …, 2024 - frontiersin.org
Although the pathological significance of myeloid cell heterogeneity is still poorly
understood, new evidence indicates that distinct macrophage subsets are characterized by …

Enhanced Photodynamic Therapy Synergizing with Inhibition of Tumor Neutrophil Ferroptosis Boosts Anti‐PD‐1 Therapy of Gastric Cancer

X Zhu, W Zheng, X Wang, Z Li, X Shen… - Advanced …, 2024 - Wiley Online Library
For tumor treatment, the ultimate goal in tumor therapy is to eliminate the primary tumor,
manage potential metastases, and trigger an antitumor immune response, resulting in the …

Mitochondrial bioenergetics of breast cancer

T Singh, K Sharma, L Jena, P Kaur, S Singh, A Munshi - Mitochondrion, 2024 - Elsevier
Breast cancer cells exhibit metabolic heterogeneity based on tumour aggressiveness.
Glycolysis and mitochondrial respiration are two major metabolic pathways for ATP …

Navigating heme pathways: the breach of heme oxygenase and hemin in breast cancer

V Consoli, V Sorrenti, M Gulisano… - Molecular and Cellular …, 2024 - Springer
Breast cancer remains a significant global health challenge, with diverse subtypes and
complex molecular mechanisms underlying its development and progression. This review …

[HTML][HTML] Metabolic Atlas of Human Eyelid Infiltrative Basal Cell Carcinoma

Y Huang, C He, Q Hu, Z Liu, X Li, W Gao… - … & Visual Science, 2025 - tvst.arvojournals.org
Purpose: Eyelid infiltrative basal cell carcinoma (iBCC) is the most common malignant tumor
affecting the ocular adnexa, but studies on metabolic changes within its microenvironment …

Heme promotes venetoclax resistance in multiple myeloma through MEK-ERK signaling and purine biosynthesis

R Nair, AH Vu, AK Freer, KS Bhatia, D Wang… - Blood, 2024 - Elsevier
We previously demonstrated that reduced intrinsic electron transport chain (ETC) activity
predicts and promotes sensitivity to the BCL-2 antagonist, venetoclax (Ven) in multiple …

Enhancing cancer immunotherapy and antiangiogenic therapy by regulating gut microbes: Opportunities and challenges

J Xu, Y Tian, D Hu, X Yan, L Yang - MedComm–Oncology, 2024 - Wiley Online Library
As the largest microecosystem in the human body, gut microbes (GMs) and their metabolites
play an important role in regulating human health. In recent years, immune checkpoint …

[PDF][PDF] Effect of Rab8a on proliferation and migration of esophageal squamous cell carcinoma cells and its molecular mechanism

R Liu, Z Kang, T Gan, Y Wang, Z Huangfu, J Cui… - 2024 - scholar.archive.org
Purpose To explore the expression and function of Rab8a in esophageal squamous cell
carcinoma (ESCC). Methods The study rst used TIMER, GEPIA and UALCAN to analyze the …