Viral vectored vaccines: design, development, preventive and therapeutic applications in human diseases
S Wang, B Liang, W Wang, L Li, N Feng… - Signal transduction and …, 2023 - nature.com
Human diseases, particularly infectious diseases and cancers, pose unprecedented
challenges to public health security and the global economy. The development and …
challenges to public health security and the global economy. The development and …
Emerging nano-/biotechnology drives oncolytic virus-activated and combined cancer immunotherapy
C Fang, G Xiao, T Wang, L Song, B Peng, B Xu… - Research, 2023 - spj.science.org
Oncolytic viruses (OVs) as one promising antitumor methods have made important
contributions to tumor immunotherapy, which arouse increasing attention. They provide the …
contributions to tumor immunotherapy, which arouse increasing attention. They provide the …
Ebola virus disease vaccines: development, current perspectives & challenges
The global outgoing outbreaks of Ebola virus disease (EVD) in different regions of Sudan,
Uganda, and Western Africa have brought into focus the inadequacies and restrictions of pre …
Uganda, and Western Africa have brought into focus the inadequacies and restrictions of pre …
Towards detection and diagnosis of Ebola virus disease at point-of-care
Ebola outbreak-2014 (mainly Zaire strain related Ebola virus) has been declared most
widely spread deadly persistent epidemic due to unavailability of rapid diagnostic, detection …
widely spread deadly persistent epidemic due to unavailability of rapid diagnostic, detection …
Post-exposure treatments for Ebola and Marburg virus infections
RW Cross, CE Mire, H Feldmann… - Nature Reviews Drug …, 2018 - nature.com
The filoviruses—Ebola virus and Marburg virus—cause lethal haemorrhagic fever in
humans and non-human primates (NHPs). Filoviruses present a global health threat both as …
humans and non-human primates (NHPs). Filoviruses present a global health threat both as …
Matrix-M adjuvant enhances antibody, cellular and protective immune responses of a Zaire Ebola/Makona virus glycoprotein (GP) nanoparticle vaccine in mice
KL Bengtsson, H Song, L Stertman, Y Liu, DC Flyer… - Vaccine, 2016 - Elsevier
Ebola virus (EBOV) causes severe hemorrhagic fever for which there is no approved
treatment or preventive vaccine. Immunological correlates of protective immunity against …
treatment or preventive vaccine. Immunological correlates of protective immunity against …
Novel technology for storage and distribution of live vaccines and other biological medicines at ambient temperature
I Bajrovic, SC Schafer, DK Romanovicz, MA Croyle - Science Advances, 2020 - science.org
A novel, thin-film platform that preserves live viruses, bacteria, antibodies, and enzymes
without refrigeration for extended periods of time is described. Studies with recombinant …
without refrigeration for extended periods of time is described. Studies with recombinant …
Ebola and Marburg virus vaccines
P Reynolds, A Marzi - Virus Genes, 2017 - Springer
The filoviruses, Ebola virus (EBOV), and Marburg virus (MARV), are among the most
pathogenic viruses known to man and the causative agents of viral hemorrhagic fever …
pathogenic viruses known to man and the causative agents of viral hemorrhagic fever …
Ebola: lessons on vaccine development
H Feldmann, F Feldmann, A Marzi - Annual review of …, 2018 - annualreviews.org
The West African Ebola virus (EBOV) epidemic has fast-tracked countermeasures for this
rare, emerging zoonotic pathogen. Until 2013–2014, most EBOV vaccine candidates were …
rare, emerging zoonotic pathogen. Until 2013–2014, most EBOV vaccine candidates were …
Clinical development of Ebola vaccines
S Sridhar - Therapeutic advances in vaccines, 2015 - journals.sagepub.com
The ongoing outbreak of Ebola virus disease in West Africa highlighted the lack of a
licensed drug or vaccine to combat the disease and has renewed the urgency to develop a …
licensed drug or vaccine to combat the disease and has renewed the urgency to develop a …