The role of MIF and IL-10 as molecular Yin-Yang in the modulation of the host immune microenvironment during infections: African trypanosome infections as a …

B Stijlemans, M Schoovaerts, P De Baetselier… - Frontiers in …, 2022 - frontiersin.org
African trypanosomes are extracellular flagellated unicellular protozoan parasites
transmitted by tsetse flies and causing Sleeping Sickness disease in humans and Nagana …

Cytokines in sepsis: friend or enemy?

SR Senousy, AS Ahmed, M El-Daly… - Journal of advanced …, 2022 - journals.ekb.eg
Infectious diseases are a major cause of death worldwide. A serious complication of
infections is septic shock. Septic shock is a critical syndrome associated with the host …

Exploring the potential mechanism of emetine against coronavirus disease 2019 combined with lung adenocarcinoma: bioinformatics and molecular simulation …

K Zhang, K Wang, C Zhang, X Teng, D Li, M Chen - BMC cancer, 2022 - Springer
Background Patients with lung adenocarcinoma (LUAD) may be more predisposed to
coronavirus disease 2019 (COVID-19) and have a poorer prognosis. Currently, there is still …

A gene regulatory network–aware graph learning method for cell identity annotation in single-cell RNA-seq data

M Zhao, J Li, X Liu, K Ma, J Tang, F Guo - Genome Research, 2024 - genome.cshlp.org
Cell identity annotation for single-cell transcriptome data is a crucial process for constructing
cell atlases, unraveling pathogenesis, and inspiring therapeutic approaches. Currently, the …

Association of ACE ID, MTHFR C677T, and MIF-173GC variants with the clinical course of COVID-19 patients

A Tekcan, M Cihangiroglu, M Capraz… - … Nucleotides & Nucleic …, 2023 - Taylor & Francis
The course of coronavirus disease-2019 (COVID-19) differs from person to person. The
relationship between the genetic variations of the host and the course of COVID-19 has …

Analyzing network diversity of cell–cell interactions in COVID-19 using single-cell transcriptomics

X Wang, AA Almet, Q Nie - Frontiers in Genetics, 2022 - frontiersin.org
Cell–cell interactions (CCI) play significant roles in manipulating biological functions of cells.
Analyzing the differences in CCI between healthy and diseased conditions of a biological …

The Role of Macrophage Migration Inhibitory Factor (MIF) and D-Dopachrome Tautomerase (D-DT/MIF-2) in Infections: A Clinical Perspective

D Breidung, IF Megas, DL Freytag, J Bernhagen… - Biomedicines, 2023 - mdpi.com
Macrophage migration inhibitory factor (MIF) and its homolog, D-dopachrome tautomerase
(D-DT), are cytokines that play critical roles in the immune response to various infectious …

Identifying novel host-based diagnostic biomarker panels for COVID-19: a whole-blood/nasopharyngeal transcriptome meta-analysis

S Maleknia, MJ Tavassolifar, F Mottaghitalab… - Molecular …, 2022 - Springer
Background Regardless of improvements in controlling the COVID-19 pandemic, the lack of
comprehensive insight into SARS-COV-2 pathogenesis is still a sophisticated challenge. In …

Biomarcadores laboratoriais na covid-19 como norteadores para plano de cuidados de enfermagem: estudo de revisão

SM dos Santos Costa… - Revista Baiana de …, 2023 - revbaianaenferm.ufba.br
Objetivo: pesquisar, na literatura, o perfil laboratorial dos pacientes acometidos gravemente
pela COVID-19, bem como organizar um plano de cuidados de enfermagem de acordo com …

[HTML][HTML] Increasing Levels of Macrophage Migration Inhibitory Factor in COVID-19 Infection and Its Pathophysiological Role; Cut-off Value Determination Might Be …

F Farzad, N Yaghoubi, FZ Avval… - Archives of Clinical …, 2023 - brieflands.com
Background: The serious outbreak of coronavirus disease 2019 (COVID-19) has provoked
deep concern throughout the world. The pathophysiologic network leading to severe …