Primary aldosteronism is a common cause of secondary hypertension associated with
excess cardiovascular morbidities. Primary aldosteronism is underdiagnosed because it …

We are witnessing a revolution in our understanding of primary aldosteronism (PA). In the
past 2 decades, we have learned that PA is a highly prevalent syndrome that is largely …

Objective Develop a consensus for the nomenclature and definition of adrenal
histopathologic features in unilateral primary aldosteronism (PA). Context Unilateral PA is …

Early diagnosis and appropriate treatment of primary aldosteronism, the most frequent
cause of secondary hypertension, are crucial to prevent deleterious cardiovascular …

Primary aldosteronism is considered the commonest cause of secondary hypertension. In
affected individuals, aldosterone is produced in an at least partially autonomous fashion in …

Aldosterone-producing adenoma (APA) cause primary aldosteronism—the most frequent
form of secondary hypertension. Somatic mutations in genes coding for ion channels and …

Primary aldosteronism (PA) is the most common form of secondary hypertension. Mutations
in KCNJ5, ATP1A1, ATP2B3 and CACNA1D are found in aldosterone producing adenoma …

Primary aldosteronism is the most common single cause of hypertension and is potentially
curable when only one adrenal gland is the culprit. The importance of primary aldosteronism …

The identification of several germline and somatic ion channel mutations in aldosterone-
producing adenomas (APAs) and detection of cell clusters that can be responsible for …

Background/Purpose Even though the increasing clinical recognition of primary
aldosteronism (PA) as a public health issue, its heightened risk profiles and the availability …