Olfactory dysfunction as an early biomarker in Parkinson's disease

ME Fullard, JF Morley, JE Duda - Neuroscience bulletin, 2017 - Springer
Olfactory dysfunction is common in Parkinson's disease (PD) and often predates the
diagnosis by years, reflecting early deposition of Lewy pathology, the histologic hallmark of …

The influences of age on olfaction: a review

RL Doty, V Kamath - Frontiers in psychology, 2014 - frontiersin.org
Decreased olfactory function is very common in the older population, being present in over
half of those between the ages of 65 and 80 years and in over three quarters of those over …

Olfactory dysfunction in neurodegenerative diseases

C Marin, D Vilas, C Langdon, I Alobid… - Current allergy and …, 2018 - Springer
Abstract Purpose of Review The sense of smell is today one of the focuses of interest in
aging and neurodegenerative disease research. In several neurodegenerative diseases …

Olfactory bulb involvement in neurodegenerative diseases

J Attems, L Walker, KA Jellinger - Acta neuropathologica, 2014 - Springer
Olfactory dysfunction is a common and early symptom of many neurodegenerative diseases,
particularly of Parkinson's disease and other synucleinopathies, Alzheimer's disease (AD) …

Neurons, nose, and neurodegenerative diseases: olfactory function and cognitive impairment

I Fatuzzo, GF Niccolini, F Zoccali, L Cavalcanti… - International Journal of …, 2023 - mdpi.com
Olfactory capacity declines with aging, but increasing evidence shows that smell dysfunction
is one of the early signs of prodromal neurodegenerative diseases such as Alzheimer's and …

Recent advances in the pathology of prodromal non-motor symptoms olfactory deficit and depression in Parkinson's disease: clues to early diagnosis and effective …

Y Bang, J Lim, HJ Choi - Archives of pharmacal research, 2021 - Springer
Parkinson's disease (PD) is a progressive neurodegenerative disease characterized by
movement dysfunction due to selective degeneration of dopaminergic neurons in the …

Adult neurogenesis in Parkinson's disease

F Marxreiter, M Regensburger, J Winkler - Cellular and Molecular Life …, 2013 - Springer
Abstract Parkinson's disease (PD), the second most common neurodegenerative disorder,
affects 1–2% of humans aged 60 years and older. The diagnosis of PD is based on motor …

Dietary factors in the etiology of Parkinson's disease

ZS Agim, JR Cannon - BioMed research international, 2015 - Wiley Online Library
Parkinson's disease (PD) is the second most common neurodegenerative disorder. The
majority of cases do not arise from purely genetic factors, implicating an important role of …

Potential convergence of olfactory dysfunction in Parkinson's disease and COVID-19: The role of neuroinflammation

H Li, J Qian, Y Wang, J Wang, X Mi, L Qu… - Ageing Research …, 2024 - Elsevier
Parkinson's disease (PD) is a prevalent neurodegenerative disorder that affects 7-10 million
individuals worldwide. A common early symptom of PD is olfactory dysfunction (OD), and …

Chemosensory dysfunction in neurodegenerative diseases

RL Doty, CH Hawkes - Handbook of clinical neurology, 2019 - Elsevier
A number of neurodegenerative diseases are accompanied by disordered smell function.
The degree of dysfunction can vary among different diseases, such that olfactory testing can …