Function of TRP channels in monocytes/macrophages

J Wu, Z Li, Y Deng, X Lu, C Luo, X Mu, T Zhang… - Frontiers in …, 2023 - frontiersin.org
The transient receptor potential channel (TRP channel) family is a kind of non-specific cation
channel widely distributed in various tissues and organs of the human body, including the …

Pathophysiological significance and modulation of the transient receptor potential canonical 3 ion channel

VK Boda, N Yasmen, J Jiang… - Medicinal Research …, 2024 - Wiley Online Library
Transient receptor potential canonical 3 (TRPC3) protein belongs to the TRP family of
nonselective cation channels. Its activation occurs by signaling through a G protein‐coupled …

Haploinsufficiency of Lipin3 leads to hypertriglyceridemia and obesity by disrupting the expression and nucleocytoplasmic localization of Lipin1

F Wang, Y Liu, Y Dong, M Zhao, H Huang, J Jin… - Frontiers of …, 2024 - Springer
Lipin proteins including Lipin 1–3 act as transcriptional co-activators and phosphatidic acid
phosphohydrolase enzymes, which play crucial roles in lipid metabolism. However, little is …

The Role of TRP Channels in Sepsis and Colitis

KA Dvornikova, ON Platonova, EY Bystrova - International Journal of …, 2024 - mdpi.com
To date, several members of the transient receptor potential (TRP) channels which provide a
wide array of roles have been found in the gastrointestinal tract (GI). The goal of earlier …

TRPC3: how current mechanistic understanding provides a basis for therapeutic targeting

K Groschner - Expert Opinion on Therapeutic Targets, 2024 - Taylor & Francis
Introduction Intensive and detailed investigations of the molecular function and cellular role
of mammalian transient receptor potential canonical (TRPC) channels started back in the …

TRP Ion Channels in Immune Cells and Their Implications for Inflammation

Q Yan, C Gao, M Li, R Lan, S Wei, R Fan… - International Journal of …, 2024 - mdpi.com
The transient receptor potential (TRP) ion channels act as cellular sensors and mediate a
plethora of physiological processes, including somatosensation, proliferation, apoptosis …

Monoacylglycerol acyltransferase maintains ionotropic receptor expression for cool temperature sensing and avoidance in Drosophila

X Deng, T Suito, M Tominaga, T Sokabe - bioRxiv, 2024 - biorxiv.org
Sensory inputs of temperature dynamics in the environment are essential for appropriate
physiological outputs. The responsiveness of sensory neurons is maintained by functional …

Effect and mechanism of transient receptor potential canonical channel 3 on hyperoxic lung injury in neonatal rats

X Fu, X Gong, T Wu, L Chen, Z Fu, C Shu - Pediatric Discovery, 2024 - Wiley Online Library
The aim of this study is to research the expression of the transient receptor potential
canonical channel 3 (TRPC3) in a neonatal hyperoxic lung injury model of …

[PDF][PDF] Metabolismo y regulación de los plasmalógenos en inmunidad innata e inflamación. Papel de la filipina-2–R

J Balsinde - 2024 - balsinde.org
La lipina-2 es una fosfatasa de ácido fosfatídico dependiente de Mg2+ que participa en la
ruta de novo de la biosíntesis de fosfolípidos. Esta enzima está ocupando en los últimos …

[PDF][PDF] Señalización mediada por lípidos en inmunidad innata e inflamación

JB Rodríguez - 2024 - balsinde.org
Los lípidos desempeñan papeles fundamentales en la regulación de la señalización celular
y los desequilibrios en su metabolismo causan una gran cantidad de enfermedades, entre …