Mental illness modeling is still a major challenge for scientists. Animal models of
schizophrenia are essential to gain a better understanding of the disease etiopathology and …

Schizophrenia is a heterogeneous psychiatric disorder that is poorly treated with current
therapies. In this brief review, we provide an update regarding the use of animal models to …

Maternal immune activation (MIA) in response to a viral infection during early and mid-
gestation has been linked through various epidemiological studies to a higher risk for the …

The hippocampus and prefrontal cortex (PFC) have long been known to play a central role
in various behavioral and cognitive functions. More recently, electrophysiological and …

Abnormalities in prefrontal gamma aminobutyric acid (GABA) ergic transmission, particularly
in fast-spiking interneurons that express parvalbumin (PV), are hypothesized to contribute to …

Converging lines of evidence from basic science and clinical studies suggest a relationship
between maternal immune activation (MIA) and neurodevelopmental disorders such as …

Maternal immune activation (mIA) during pregnancy is hypothesised to disrupt offspring
neurodevelopment and predispose offspring to neurodevelopmental disorders such as …

Prenatal exposure to infectious or inflammatory insults can increase the risk of developing
neuropsychiatric disorder in later life, including schizophrenia, bipolar disorder, and autism …

Mothers exposed to infections during pregnancy disproportionally birth children who
develop autism and schizophrenia, disorders associated with altered GABAergic function …

Background Prenatal exposure to infection and/or inflammation is increasingly recognized to
play an important role in neurodevelopmental brain disorders. It has recently been …