Tocilizumab in the treatment of rheumatoid arthritis: an evidence-based review and patient selection

M Biggioggero, C Crotti, A Becciolini… - Drug design …, 2018 - Taylor & Francis
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by articular and
systemic manifestations, such as anemia, fatigue, osteoporosis, and increased risk for …

Comparative risk of cardiovascular events with biologic and synthetic disease‐modifying antirheumatic drugs in patients with rheumatoid arthritis: a systematic review …

S Singh, M Fumery, AG Singh, N Singh… - Arthritis care & …, 2020 - Wiley Online Library
Objective We performed a systematic review and meta‐analysis to evaluate the comparative
effects of tumor necrosis factor inhibitors (TNF i), non‐TNF i biologics, and conventional …

Antibody-based therapeutics for atherosclerosis and cardiovascular diseases

E Ji, S Lee - International Journal of Molecular Sciences, 2021 - mdpi.com
Cardiovascular disease is the leading cause of death worldwide, and its prevalence is
increasing due to the aging of societies. Atherosclerosis, a type of chronic inflammatory …

A systematic literature review informing the consensus statement on efficacy and safety of pharmacological treatment with interleukin-6 pathway inhibition with …

K Kastrati, D Aletaha, GR Burmester, E Chwala… - RMD open, 2022 - rmdopen.bmj.com
Objectives Informing an international task force updating the consensus statement on
efficacy and safety of biological disease-modifying antirheumatic drugs (bDMARDs) …

[HTML][HTML] Beyond Lipoprotein (a) plasma measurements: Lipoprotein (a) and inflammation

G Reyes-Soffer, M Westerterp - Pharmacological research, 2021 - Elsevier
Genome wide association, epidemiological, and clinical studies have established high
lipoprotein (a)[Lp (a)] as a causal risk factor for atherosclerotic cardiovascular disease …

Rheumatoid arthritis and cardiovascular risk: retrospective matched-cohort analysis based on the RECORD study of the Italian Society for Rheumatology

L Argnani, A Zanetti, G Carrara, E Silvagni… - Frontiers in …, 2021 - frontiersin.org
Background: Rheumatoid arthritis (RA) is associated with an increase in cardiovascular (CV)
risk. This issue maybe not only explained by a genetic component, as well as by the …

Anticytokine immune therapy and atherothrombotic cardiovascular risk

H Ait-Oufella, P Libby, A Tedgui - Arteriosclerosis, thrombosis, and …, 2019 - Am Heart Assoc
Accumulating observations in humans and animals indicate that inflammation plays a key
role in atherosclerosis development and subsequent complications. Moreover, the use of …

Comparative effectiveness of first-line biological monotherapy use in rheumatoid arthritis: a retrospective analysis of the RECord-linkage On Rheumatic Diseases …

E Silvagni, A Bortoluzzi, G Carrara, A Zanetti… - BMJ open, 2018 - bmjopen.bmj.com
Objective These analyses aim to comparatively evaluate the persistence on treatment of
different biological disease-modifying antirheumatic drugs (bDMARDs) when administered …

Risk of hospitalisation for serious bacterial infections in patients with rheumatoid arthritis treated with biologics. Analysis from the RECord linkage On Rheumatic …

G Carrara, A Bortoluzzi, G Sakellariou… - Clinical and …, 2019 - boa.unimib.it
Objective The aims of this study were to define the risk of serious bacterial infections in
patients receiving specific biological disease-modifying anti-rheumatic drugs (bDMARDs) …

One year in review 2018: novelties in the treatment of rheumatoid arthritis

A Bortoluzzi, F Furini, E Generali, E Silvagni… - Clinical and …, 2018 - boa.unimib.it
The current approach to treatment of rheumatoid arthritis (RA) includes early and aggressive
intervention aiming to reach early and persistent low disease activity and remission. New …