Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of the global obesity
and metabolic disease epidemic and is rapidly becoming the leading cause of liver cirrhosis …

Background: Metabolic syndrome is a combination of dysregulated cardiometabolic risk
factors characterized by dyslipidemia, impaired glucose tolerance, insulin resistance …

NRF2 (nuclear factor erythroid 2-related factor 2) is a key transcriptional activator that
mediates the inducible expression of antioxidant genes. NRF2 is normally ubiquitinated by …

Nonalcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease.
NAFLD often occurs associated with endocrinopathies. Evidence suggests that endocrine …

An increased risk of obesity has become a common public health concern as it is associated
with hypertension, diabetes, osteoarthritis, heart diseases, liver steatosis etc …

Non-alcoholic fatty liver disease (NAFLD) is a spectrum of disease spanning from simple
benign steatosis to steatohepatitis with fibrosis and scarring that can eventually lead to …

In the normal liver, cells interact closely through gap junctions. By providing a pathway for
the trafficking of low molecular mass molecules, these channels contribute to tissue …

Objectives To determine the efficacy of Corchorus olitorius (C. olitorius) leaf extract in the
prevention of metabolic syndrome induced in rats by high-fat diet (HFD) and compare it with …

Abstract Context: Piper nigrum Linn (Piperaceae)(PnL) is used in traditional medicine to
treat gastric ailments, dyslipidemia, diabetes, and hypertension. Objective: The present …

Regulating insulin and leptin levels using a protein tyrosine phosphatase 1B (PTP1B)
inhibitor is an attractive strategy to treat diabetes and obesity. Glycyrrhetinic acid (GA), a …