Cancer occurs when cells acquire genomic instability and inflammation, produce abnormal
levels of epigenetic factors/proteins and tumor suppressors, reprogram the energy …

Proper tissue function and regeneration rely on robust spatial and temporal control of
biophysical and biochemical microenvironmental cues through mechanisms that remain …

The ability to three-dimensionally interweave biological tissue with functional electronics
could enable the creation of bionic organs possessing enhanced functionalities over their …

We report on a functional human model to evaluate multi-organ toxicity in a 4-organ system
under continuous flow conditions in a serum-free defined medium utilizing a pumpless …

Over this decade, cell printing strategy has emerged as one of the promising approaches to
organize cells in two and three dimensional engineered tissues. High resolution and high …

In the last decades, the basic techniques of microfluidics for the study of cells such as cell
culture, cell separation, and cell lysis, have been well developed. Based on cell handling …

Deciphering the multifactorial determinants of tumor progression requires standardized high-
throughput preparation of 3D in vitro cellular assays. We present a simple microfluidic …

High-throughput screening (HTS) is one of the newest techniques used in drug design and
may be applied in biological and chemical sciences. This method, due to utilization of …

The recent cataloging of the genomic aberrations in breast cancer has revealed the diversity
and complexity of the disease at the genetic level. To unravel the functional consequences …

Despite the tremendous hurdles presented by the complexity of the liver's structure and
function, advances in liver physiology, stem cell biology and reprogramming, and the …