The epithelium represents the first and most extensive line of defence against pathogens,
toxins and pollutant agents in humans. In general, pathogens have developed strategies to …

Entamoeba histolytica, the causative agent of human amoebiasis, exhibits a continuous
membrane remodelling to exert its virulence properties. During this dynamic process, the …

Lipids are essential players in parasites pathogenesis. In particular, the highly phagocytic
trophozoites of Entamoeba histolytica, the causative agent of amoebiasis, exhibit a dynamic …

Oropharyngeal mucosal epithelia of fetuses/neonates/infants and the genital epithelia of
adults play a critical role in HIV-1 mother-to-child transmission and sexual transmission of …

The endosomal sorting complex required for transport (ESCRT) is formed by ESCRT-0,
ESCRT-I, ESCRT-II, ESCRT-III complexes, and accessory proteins. It conducts vesicular …

The EhVps23 protein, an orthologue of the yeast Vps23 and the mammalian TSG101
proteins, is the single member of the ESCRT-I complex of Entamoeba histolytica identified …

Entamoeba histolytica, the highly phagocytic protozoan causative of human amoebiasis
lacks the machinery to synthesize cholesterol. Here, we investigated the presence of NPC1 …

Movement and phagocytosis are clue events in colonisation and invasion of tissues by
Entamoeba histolytica, the protozoan causative of human amoebiasis. During phagocytosis …

In Entamoeba histolytica, the EhADH adhesin together with the EhCP112 cysteine protease,
form a 124 kDa complex named EhCPADH. This complex participates in trophozoite …

Eukaryotic cells are organized into separate membrane-bound compartments that have
specialized biochemical signature and function. Maintenance and regulation of distinct …