Remarkable interest has risen in the idea that oxidative/nitrosative stress is mediated in the
etiology of numerous human diseases. Oxidative/Nitrosative stress is the result of an …

Invasive fungal diseases (IFDs) are devastating opportunistic infections that result in
significant morbidity and death in a broad range of pediatric patients, particularly those with …

Chronic granulomatous disease (CGD) is an innate immunodeficiency with a genetic defect
of the nicotinamide adenosine dinucleotide phosphate, reduced, oxidase components. This …

Plant phenolics are secondary metabolites of plants which have different functions in
plantlike giving color and odor to the fruit and flower, defense against biotic and abiotic …

Purpose Clinical diagnosis and treatment for chronic granulomatous disease (CGD) have
advanced greatly in recent years. However, CGD patients in China have unique clinical …

The primary immunodeficiencies (PIDs), rare inherited diseases characterized by severe
dysfunction of immunity, have been successfully treated by allogeneic hematopoietic stem …

Cellular metabolism influences immune cell function, with mitochondrial fatty acid β-
oxidation and oxidative phosphorylation required for multiple immune cell phenotypes …

Patients with chronic granulomatous disease (CGD) have the highest life-time incidence of
invasive aspergillosis and despite the availability of antifungal prophylaxis, infections by …

Background Chronic granulomatous disease (CGD) is an inborn error of immunity caused
by defects in the phagocytic nicotinamide adenine dinucleotide phosphate oxidase complex …

Neutrophils are key to host defence, and impaired neutrophil function predisposes to
infection with an array of pathogens, with Staphylococcus aureus a common and sometimes …