The application of long-read sequencing in clinical settings
Long-read DNA sequencing technologies have been rapidly evolving in recent years, and
their ability to assess large and complex regions of the genome makes them ideal for clinical …
their ability to assess large and complex regions of the genome makes them ideal for clinical …
Clinical Diagnostics of Bacterial Infections and Their Resistance to Antibiotics—Current State and Whole Genome Sequencing Implementation Perspectives
Antimicrobial resistance (AMR), defined as the ability of microorganisms to withstand
antimicrobial treatment, is responsible for millions of deaths annually. The rapid spread of …
antimicrobial treatment, is responsible for millions of deaths annually. The rapid spread of …
SERS nanowire chip and machine learning-enabled classification of wild-type and antibiotic-resistant bacteria at species and strain levels
Antimicrobial resistance (AMR) is a major health threat worldwide and the culture-based
bacterial detection methods are slow. Surface-enhanced Raman spectroscopy (SERS) can …
bacterial detection methods are slow. Surface-enhanced Raman spectroscopy (SERS) can …
Nanopore-only assemblies for genomic surveillance of the global priority drug-resistant pathogen, Klebsiella pneumoniae
Oxford Nanopore Technologies (ONT) sequencing has rich potential for genomic
epidemiology and public health investigations of bacterial pathogens, particularly in low …
epidemiology and public health investigations of bacterial pathogens, particularly in low …
Highly sensitive quantitative phase microscopy and deep learning aided with whole genome sequencing for rapid detection of infection and antimicrobial resistance
Current state-of-the-art infection and antimicrobial resistance (AMR) diagnostics are based
on culture-based methods with a detection time of 48–96 h. Therefore, it is essential to …
on culture-based methods with a detection time of 48–96 h. Therefore, it is essential to …
Ultrafast and cost-effective pathogen identification and resistance gene detection in a clinical setting using nanopore flongle sequencing
E Avershina, SA Frye, J Ali, AM Taxt… - Frontiers in …, 2022 - frontiersin.org
Rapid bacterial identification and antimicrobial resistance gene (ARG) detection are crucial
for fast optimization of antibiotic treatment, especially for septic patients where each hour of …
for fast optimization of antibiotic treatment, especially for septic patients where each hour of …
A culture-, amplification-independent, and rapid method for identification of pathogens and antibiotic resistance profile in bovine mastitis milk
Introduction Rapid and accurate diagnosis of causative pathogens in mastitis would
minimize the imprudent use of antibiotics and, therefore, reduce the spread of antimicrobial …
minimize the imprudent use of antibiotics and, therefore, reduce the spread of antimicrobial …
Co-Existence of blaNDM-1, blaOXA-23, blaOXA-64, blaPER-7 and blaADC-57 in a Clinical Isolate of Acinetobacter baumannii from Alexandria, Egypt
S Sánchez-Urtaza, A Ocampo-Sosa… - International Journal of …, 2023 - mdpi.com
The increasing rates of antimicrobial resistance among carbapenem-resistant Acinetobacter
baumannii in the Middle East and North Africa are one of the major concerns for healthcare …
baumannii in the Middle East and North Africa are one of the major concerns for healthcare …
The impact of applying various de novo assembly and correction tools on the identification of genome characterization, drug resistance, and virulence factors of …
HA Safar, F Alatar, K Nasser, R Al-Ajmi, W Alfouzan… - BMC …, 2023 - Springer
Oxford Nanopore sequencing technology (ONT) is currently widely used due to its
affordability, simplicity, and reliability. Despite the advantage ONT has over next-generation …
affordability, simplicity, and reliability. Despite the advantage ONT has over next-generation …
Short turnaround time of seven to nine hours from sample collection until informed decision for sepsis treatment using nanopore sequencing
Bloodstream infections (BSIs) and sepsis are major health problems, annually claiming
millions of lives. Traditional blood culture techniques, employed to identify sepsis-causing …
millions of lives. Traditional blood culture techniques, employed to identify sepsis-causing …