Insulin signaling requires glucose to promote lipid anabolism in adipocytes
Adipose tissue is essential for metabolic homeostasis, balancing lipid storage and
mobilization based on nutritional status. This is coordinated by insulin, which triggers kinase …
mobilization based on nutritional status. This is coordinated by insulin, which triggers kinase …
Lactate production is a prioritized feature of adipocyte metabolism
Adipose tissue is essential for whole-body glucose homeostasis, with a primary role in lipid
storage. It has been previously observed that lactate production is also an important …
storage. It has been previously observed that lactate production is also an important …
[HTML][HTML] Measuring metabolic rate in single flies during sleep and waking states via indirect calorimetry
Background Drosophila melanogaster is a leading genetic model for studying the neural
regulation of sleep. Sleep is associated with changes in behavior and physiological state …
regulation of sleep. Sleep is associated with changes in behavior and physiological state …
Genome-wide analysis in Drosophila reveals diet-by-gene interactions and uncovers diet-responsive genes
D Francis, S Ghazanfar, E Havula, JR Krycer… - G3, 2021 - academic.oup.com
Genetic and environmental factors play a major role in metabolic health. However, they do
not act in isolation, as a change in an environmental factor such as diet may exert different …
not act in isolation, as a change in an environmental factor such as diet may exert different …
A cell culture platform for quantifying metabolic substrate oxidation in bicarbonate-buffered medium
JR Krycer, M Lor, RL Fitzsimmons… - Journal of Biological …, 2022 - ASBMB
Complex diseases such as cancer and diabetes are underpinned by changes in
metabolism, specifically by which and how nutrients are catabolized. Substrate utilization …
metabolism, specifically by which and how nutrients are catabolized. Substrate utilization …
Measuring metabolic rate in single flies during sleep and waking states
Drosophila melanogaster is a leading genetic model for studying the neural regulation of
sleep. Sleep is associated with changes in behavior and physiological state that are largely …
sleep. Sleep is associated with changes in behavior and physiological state that are largely …
Genome-wide analysis of diet and gene interactions in Drosophila uncovers the glucose transporter, CG4607, as a diet-responsive gene
It is clear that both genetic and environmental factors contribute to metabolic health.
However, they do not act in isolation. Here, we sought to understand how the interaction …
However, they do not act in isolation. Here, we sought to understand how the interaction …
[PDF][PDF] James R. Krycer1, 2, Lake-Ee Quek2, 4, Deanne Francis1, 2, Daniel J. Fazakerley1, 2, 5, Sarah D. Elkington1, 2, Alexis Diaz-Vegas1, 2, Kristen C. Cooke1, 2 …
TS Kamei, GJ Cooney - academia.edu
* To whom correspondence should be addressed: David E. James: Charles Perkins Centre,
The University of Sydney, Sydney, NSW, 2006, Australia; david. james@ sydney. edu. au; …
The University of Sydney, Sydney, NSW, 2006, Australia; david. james@ sydney. edu. au; …