Spinal cord injury: molecular mechanisms and therapeutic interventions

X Hu, W Xu, Y Ren, Z Wang, X He, R Huang… - Signal transduction and …, 2023 - nature.com
Spinal cord injury (SCI) remains a severe condition with an extremely high disability rate.
The challenges of SCI repair include its complex pathological mechanisms and the …

Immunomodulatory hydrogels: advanced regenerative tools for diabetic foot ulcer

Y Xiong, Q Feng, L Lu, K Zha, T Yu, Z Lin… - Advanced Functional …, 2023 - Wiley Online Library
Diabetic foot ulcer (DFU) is one of the most common complications of diabetes, bringing
physical and mental challenges for patients due to the lack of efficient curative therapy …

Adhesive, stretchable, and spatiotemporal delivery fibrous hydrogels harness endogenous neural stem/progenitor cells for spinal cord injury repair

Z Chen, H Zhang, C Fan, Y Zhuang, W Yang, Y Chen… - ACS …, 2021 - ACS Publications
Aligned fibrous hydrogels capable of recruiting endogenous neural stem/progenitor cells
(NSPCs) show great promise in spinal cord injury (SCI) repair. However, the hydrogels …

Applications of chitosan-based biomaterials: From preparation to spinal cord injury neuroprosthetic treatment

W Xiang, H Cao, H Tao, L Jin, Y Luo, F Tao… - International Journal of …, 2023 - Elsevier
Spinal cord injury (SCI)-related disabilities are a serious problem in the modern society.
Further, the treatment of SCI is highly challenging and is urgently required in clinical …

Therapeutic options and drug delivery strategies for the prevention of intrauterine adhesions

L Kou, X Jiang, S Xiao, YZ Zhao, Q Yao… - Journal of Controlled …, 2020 - Elsevier
Intrauterine adhesions (IUAs) are bands of fibrous tissue that form in the endometrial cavity
and associated with the increased risk of abnormal menstruation, recurrent pregnancy loss …

[HTML][HTML] Neural tissue engineering with structured hydrogels in CNS models and therapies

J George, CC Hsu, LTB Nguyen, H Ye, Z Cui - Biotechnology advances, 2020 - Elsevier
The development of techniques to create and use multiphase microstructured hydrogels
(granular hydrogels or microgels) has enabled the generation of cultures with more …

[HTML][HTML] Functional hydrogels as therapeutic tools for spinal cord injury: New perspectives on immunopharmacological interventions

CM Walsh, JK Wychowaniec, DF Brougham… - Pharmacology & …, 2022 - Elsevier
Spinal cord injury (SCI) is a complex medical and psychological challenge for which there is
no curative therapy currently available. Despite major progress in pharmacological and …

Combining stem cells and biomaterial scaffolds for constructing tissues and cell delivery

SM Willerth, SE Sakiyama-Elbert - StemJournal, 2019 - content.iospress.com
Combining stem cells with biomaterial scaffolds serves as a promising strategy for
engineering tissues for both in vitro and in vivo applications. This updated review details …

Is graphene shortening the path toward spinal cord regeneration?

AF Girão, MC Serrano, A Completo, PAAP Marques - ACS nano, 2022 - ACS Publications
Along with the development of the next generation of biomedical platforms, the inclusion of
graphene-based materials (GBMs) into therapeutics for spinal cord injury (SCI) has potential …

[HTML][HTML] Recent developments in bio-scaffold materials as delivery strategies for therapeutics for endometrium regeneration

X Li, HF Lv, R Zhao, M Ying, AT Samuriwo, YZ Zhao - Materials Today Bio, 2021 - Elsevier
Intrauterine adhesions (IUAs) refer to the repair disorder after endometrial injury and may
lead to uterine infertility, recurrent miscarriage, abnormal menstrual bleeding, and other …