[HTML][HTML] Kynurenic Acid/AhR Signaling at the Junction of Inflammation and Cardiovascular Diseases
AY Grishanova, ML Perepechaeva - International Journal of Molecular …, 2024 - mdpi.com
Persistent systemic chronic inflammatory conditions are linked with many pathologies,
including cardiovascular diseases (CVDs), a leading cause of death across the globe …
including cardiovascular diseases (CVDs), a leading cause of death across the globe …
[HTML][HTML] Integrated metabolomics and proteomics reveal biomarkers associated with hemodialysis in end-stage kidney disease
Background: We hypothesize that the poor survival outcomes of end-stage kidney disease
(ESKD) patients undergoing hemodialysis are associated with a low filtering efficiency and …
(ESKD) patients undergoing hemodialysis are associated with a low filtering efficiency and …
[HTML][HTML] Circulating glutamine/glutamate ratio is closely associated with type 2 diabetes and its associated complications
F Han, C Xu, X Hangfu, Y Liu, Y Zhang… - Frontiers in …, 2024 - frontiersin.org
Objective This study aims to conduct a comprehensive investigation of the serum amino acid
profiles of individuals with type 2 diabetes (T2D) and its related complications. Methods …
profiles of individuals with type 2 diabetes (T2D) and its related complications. Methods …
ACMSD mediated de novo NAD+ biosynthetic impairment in cardiac endothelial cells as a potential therapeutic target for diabetic cardiomyopathy
F Zeng, P Zhou, M Wang, L Xie, X Huang… - Diabetes Research and …, 2023 - Elsevier
Object The highly conserved α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase
(ACMSD) is the key enzyme that regulates the de novo NAD+ synthesis from tryptophan …
(ACMSD) is the key enzyme that regulates the de novo NAD+ synthesis from tryptophan …
Altered neopterin and IDO in kynurenine metabolism based on LC-MS/MS metabolomics study: Novel therapeutic checkpoints for type 2 diabetes mellitus
Z Liu, Z Ma, L Jin, X Nizhamuding, J Zeng, T Zhang… - Clinica Chimica …, 2024 - Elsevier
Background This study assessed the alternations of kynurenine pathway (KP) and neopterin
in type 2 diabetes mellitus (T2DM) and explored possible differential metabolites. Methods A …
in type 2 diabetes mellitus (T2DM) and explored possible differential metabolites. Methods A …