Fibromyalgia (FM) is a syndrome that does not present a well-defined underlying organic
disease. FM is a condition which has been associated with diseases such as infections …

Background Chronic pain is common in adults, and often has a detrimental impact upon
physical ability, well‐being, and quality of life. Previous reviews have shown that certain …

Introduction The optimal dose of duloxetine in the management of fibromyalgia remains still
controversial. Therefore, a systematic review and meta-analysis to investigate efficacy and …

Background Duloxetine and pregabalin are among the most widely used medications in the
treatment of patients with fibromyalgia syndrome (FM). Objectives To add to the very few …

Pain can become a chronic and deliberating experience with a significant burden. In
preclinical and clinical studies, Saffron (Crocus sativus L.) has shown analgesic activities …

Psychotropic effect of Crocus sativus L.(family Iridaceae) biologically active chemical
compounds are quite well documented and they can therefore be used in addition to the …

Ethnopharmacological relevance Chemotherapy-induced peripheral neuropathy (CIPN) is
one of the complications vexes patients treated with anti-cancer agents. Saffron has been …

Immunoregulatory Effects of Krocina™, a Herbal Medicine Made of Crocin, on Osteoarthritis
Patients: A Successful Clinical Tri Page 1 Copyright© June 2020, Iran J Allergy Asthma …

Though both neuropathy and fibromyalgia are serious complications that cause widespread
pain, distinguishing between the two in order to provide adequate care is difficult. Metabolic …

Rheumatic diseases (RDs) are often complicated by chronic symptoms and frequent side-
effects associated with their treatment. Saffron, a spice derived from the Crocus sativus L …