Microbiome and human health: current understanding, engineering, and enabling technologies

N Aggarwal, S Kitano, GRY Puah, S Kittelmann… - Chemical …, 2022 - ACS Publications
The human microbiome is composed of a collection of dynamic microbial communities that
inhabit various anatomical locations in the body. Accordingly, the coevolution of the …

[HTML][HTML] Functions of gut microbiota metabolites, current status and future perspectives

J Liu, Y Tan, H Cheng, D Zhang, W Feng… - Aging and …, 2022 - ncbi.nlm.nih.gov
Gut microbiota, a collection of microorganisms that live within gastrointestinal tract, provides
crucial signaling metabolites for the physiological of hosts. In healthy state, gut microbiota …

The immune response to Prevotella bacteria in chronic inflammatory disease

JM Larsen - Immunology, 2017 - Wiley Online Library
The microbiota plays a central role in human health and disease by shaping immune
development, immune responses and metabolism, and by protecting from invading …

Immune activation, inflammation, and non-AIDS co-morbidities in HIV-infected patients under long-term ART

S Zicari, L Sessa, N Cotugno, A Ruggiero, E Morrocchi… - Viruses, 2019 - mdpi.com
Despite effective antiretroviral therapy (ART), people living with HIV (PLWH) still present
persistent chronic immune activation and inflammation. This condition is the result of several …

Plasma markers of disrupted gut permeability in severe COVID-19 patients

LB Giron, H Dweep, X Yin, H Wang, M Damra… - Frontiers in …, 2021 - frontiersin.org
A disruption of the crosstalk between the gut and the lung has been implicated as a driver of
severity during respiratory-related diseases. Lung injury causes systemic inflammation …

Incomplete immune reconstitution in HIV/AIDS patients on antiretroviral therapy: Challenges of immunological non-responders

X Yang, B Su, X Zhang, Y Liu, H Wu… - Journal of leukocyte …, 2020 - academic.oup.com
The morbidity and mortality of HIV type-1 (HIV-1)-related diseases were dramatically
diminished by the grounds of the introduction of potent antiretroviral therapy, which induces …

Functional redundancy-induced stability of gut microbiota subjected to disturbance

A Moya, M Ferrer - Trends in microbiology, 2016 - cell.com
The microbiota should be considered as just another component of the human epigenetic
landscape. Thus, health is also a reflection of the diversity and composition of gut microbiota …

Use of metatranscriptomics in microbiome research

S Bashiardes… - … and biology insights, 2016 - journals.sagepub.com
The human intestinal microbiome is a microbial ecosystem that expresses as many as 100
times more genes than the human host, thereby constituting an important component of the …

HIV and antiretroviral therapy-related fat alterations

JR Koethe, C Lagathu, JE Lake, P Domingo… - Nature reviews Disease …, 2020 - nature.com
Early in the HIV epidemic, lipodystrophy, characterized by subcutaneous fat loss
(lipoatrophy), with or without central fat accumulation (lipohypertrophy), was recognized as a …

Altered virome and bacterial microbiome in human immunodeficiency virus-associated acquired immunodeficiency syndrome

CL Monaco, DB Gootenberg, G Zhao, SA Handley… - Cell host & …, 2016 - cell.com
Human immunodeficiency virus (HIV) infection is associated with increased intestinal
translocation of microbial products and enteropathy as well as alterations in gut bacterial …