Ca2+ signaling in mammalian spermatozoa

M Finkelstein, N Etkovitz, H Breitbart - Molecular and Cellular …, 2020 - Elsevier
Calcium is an essential ion which regulates sperm motility, capacitation and the acrosome
reaction (AR), three processes necessary for successful fertilization. The AR enables the …

Odorant and taste receptors in sperm chemotaxis and cryopreservation: roles and implications in sperm capacitation, motility and fertility

MA Ali, Y Wang, Z Qin, X Yuan, Y Zhang, C Zeng - Genes, 2021 - mdpi.com
Sperm chemotaxis, which guide sperm toward oocyte, is tightly associated with sperm
capacitation, motility, and fertility. However, the molecular mechanism of sperm chemotaxis …

Capacitation promotes a shift in energy metabolism in murine sperm

M Tourmente, E Sansegundo, E Rial… - Frontiers in Cell and …, 2022 - frontiersin.org
In mammals, sperm acquire fertilization ability after a series of physiological and
biochemical changes, collectively known as capacitation, that occur inside the female …

Protoplast Isolation and Shoot Regeneration from Protoplast-Derived Callus of Petunia hybrida Cv. Mirage Rose

HH Kang, AH Naing, CK Kim - Biology, 2020 - mdpi.com
Despite the increasing use of protoplasts in plant biotechnology research, shoot
regeneration from protoplasts remains challenging. In this study, we investigated the factors …

EDC IMPACT: Chemical UV filters can affect human sperm function in a progesterone-like manner

A Rehfeld, DL Egeberg, K Almstrup… - Endocrine …, 2018 - ec.bioscientifica.com
Human sperm cell function must be precisely regulated to achieve natural fertilization.
Progesterone released by the cumulus cells surrounding the egg induces a Ca 2+ influx into …

Toxicological outcome of phthalate exposure on male fertility: Ameliorative impacts of the co-administration of N-acetylcysteine and zinc sulfate in rats

V Emojevwe, EK Nwangwa, AO Naiho… - Middle East Fertility …, 2022 - Springer
Background Reports have shown that humans are consistently exposed to environmental
toxicants such as phthalate (PHT) during their daily activities. This results in reproductive …

Protein acetylation protects sperm from spontaneous acrosome reaction

Z Bowker, S Goldstein, H Breitbart - Theriogenology, 2022 - Elsevier
In order to penetrate the egg, spermatozoa must undergo the acrosome reaction in close
proximity to the egg. This process can take place only after a series of biochemical changes …

Pyruvate modulation of redox potential controls mouse sperm motility

CA Schmidt, BJ Hale, D Bhowmick, WJ Miller… - Developmental Cell, 2024 - cell.com
Sperm gain fertilization competence in the female reproductive tract through a series of
biochemical changes and a requisite switch from linear progressive to hyperactive motility …

Involvement of metabolic pathway in the sperm spontaneous acrosome reaction

T Dahan, H Breitbart - Theriogenology, 2022 - Elsevier
In order to fertilize the egg, spermatozoa must undergo a series of biochemical processes in
the female reproductive tract collectively called capacitation. Only capacitated sperm can …

Sperm selection by the oviduct: perspectives for male fertility and assisted reproductive technologies

S Soto-Heras, D Sakkas, DJ Miller - Biology of reproduction, 2023 - academic.oup.com
The contribution of sperm to embryogenesis is gaining attention with up to 50% of infertility
cases being attributed to a paternal factor. The traditional methods used in assisted …