Composition and functions of bacterial membrane vesicles

M Toyofuku, S Schild, M Kaparakis-Liaskos… - Nature Reviews …, 2023 - nature.com
Extracellular vesicles are produced by species across all domains of life, suggesting that
vesiculation represents a fundamental principle of living matter. In Gram-negative bacteria …

Bacterial extracellular vesicles and their novel therapeutic applications in health and cancer

N Hosseini-Giv, A Basas, C Hicks, E El-Omar… - Frontiers in Cellular …, 2022 - frontiersin.org
Bacterial cells communicate with host cells and other bacteria through the release of
membrane vesicles known as bacterial extracellular vesicles (BEV). BEV are established …

Staphylococcus aureus membrane vesicles contain immunostimulatory DNA, RNA and peptidoglycan that activate innate immune receptors and induce autophagy

NJ Bitto, L Cheng, EL Johnston… - Journal of …, 2021 - Wiley Online Library
Gram‐positive bacteria ubiquitously produce membrane vesicles (MVs), and although they
contribute to biological functions, our knowledge regarding their composition and …

Diversity and versatility in small RNA-mediated regulation in bacterial pathogens

B Felden, Y Augagneur - Frontiers in Microbiology, 2021 - frontiersin.org
Bacterial gene expression is under the control of a large set of molecules acting at multiple
levels. In addition to the transcription factors (TFs) already known to be involved in global …

Extracellular vesicles and host–pathogen interactions: a review of inter-kingdom signaling by small noncoding RNA

BA Stanton - Genes, 2021 - mdpi.com
The focus of this brief review is to describe the role of noncoding regulatory RNAs, including
short RNAs (sRNA), transfer RNA (tRNA) fragments and microRNAs (miRNA) secreted in …

Temperature influences the composition and cytotoxicity of extracellular vesicles in Staphylococcus aureus

P Briaud, A Frey, EC Marino, RA Bastock, RE Zielinski… - Msphere, 2021 - Am Soc Microbiol
Staphylococcus aureus is a pathogenic bacterium but also a commensal of skin and anterior
nares in humans. As S. aureus transits from skins/nares to inside the human body, it …

Transfer RNA-derived fragments, the underappreciated regulatory small RNAs in microbial pathogenesis

Z Li, BA Stanton - Frontiers in Microbiology, 2021 - frontiersin.org
In eukaryotic organisms, transfer RNA (tRNA)-derived fragments have diverse biological
functions. Considering the conserved sequences of tRNAs, it is not surprising that …

Acute kidney injury by ischemia/reperfusion and extracellular vesicles

MØ Nørgård, P Svenningsen - International Journal of Molecular Sciences, 2023 - mdpi.com
Acute kidney injury (AKI) is often caused by ischemia-reperfusion injury (IRI). IRI significantly
affects kidney metabolism, which elicits pro-inflammatory responses and kidney injury. The …

Application of Nanomaterials in the Prevention, Detection, and Treatment of Methicillin-Resistant Staphylococcus aureus (MRSA)

J Hulme - Pharmaceutics, 2022 - mdpi.com
Due to differences in geographic surveillance systems, chemical sanitization practices, and
antibiotic stewardship (AS) implementation employed during the COVID-19 pandemic, many …

Environmental Plasticity of the RNA Content of Staphylococcus aureus Extracellular Vesicles

BSRD Luz, A Nicolas, S Chabelskaya… - Frontiers in …, 2021 - frontiersin.org
The roles of bacterial extracellular vesicles (EVs) in cell-to-cell signaling are progressively
being unraveled. These membranous spheres released by many living cells carry various …