This paper is the forty-fourth consecutive installment of the annual anthological review of
research concerning the endogenous opioid system, summarizing articles published during …

Importance High-risk infants, defined as newborns with substantial neonatal-perinatal
morbidities, often undergo multiple procedures and require prolonged intubation, resulting …

Background and aims Both local socio‐economic conditions and prescription opioid supply
are associated with drug overdose deaths, which exhibit substantial geographical …

This is the first clinical practice guideline (CPG) from the American Academy of Pediatrics
outlining evidence-based approaches to safely prescribing opioids for acute pain in …

Background There has been a recent focus among anesthesiologists on reducing the use of
perioperative opioids in favor of multimodal analgesic regimens. Gabapentin has played an …

Importance In prior studies, decreasing the default number of doses in opioid prescriptions
written in electronic health record systems reduced opioid prescribing. However, these …

Video Abstract BACKGROUND AND OBJECTIVES Surgery is one of the most common
indications for opioid prescribing to pediatric patients. We identified which procedures …

METHODS We used IQVIA National Prescription Audit Patient Insights data, which contains
prescriptions dispensed from∽ 48 900 retail pharmacies, representing 93% of all …

Background Adolescent opioid misuse has been recognized as a dire public health issue.
Despite efforts to address the opioid epidemic in the United States, opioid-related morbidity …

Abstract Background The Nuss procedure for pectus excavatum is associated with
prolonged hospitalizations due to pain. We evaluated implementation of intercostal nerve …