The human transcription factor 4 gene (TCF4) encodes a helix–loop–helix transcription
factor widely expressed throughout the body and during neural development. Mutations in …

The mesodiencephalic dopaminergic (mdDA) group of neurons comprises molecularly
distinct subgroups, of which the substantia nigra (SN) and ventral tegmental area (VTA) are …

The basic helix-loop-helix (bHLH) transcription factor genes Hand1 and Mash2 are essential
for placental development in mice. Hand1 promotes differentiation of trophoblast giant cells …

We have performed a detailed comparative in situ hybridization analysis to examine the
patterns of expression of all the members of the Id gene family (Id1–4) during marine …

Background Transcription factor 4 (TCF4 alias ITF2, E2-2, ME2 or SEF2) is a ubiquitous
class A basic helix-loop-helix protein that binds to E-box DNA sequences (CANNTG). While …

BACKGROUND: The combined analysis of several large genome-wide association studies
identified the basic helix-loop-helix (bHLH) transcription factor TCF4 as one of the most …

Terminal cell differentiation is usually associated with cell cycle exit. In some lineages,
however, cells undergo continued rounds of DNA synthesis without intervening mitoses …

Schizophrenia is a genetically complex disease considered to have a neurodevelopmental
pathogenesis and defined by a broad spectrum of positive and negative symptoms as well …

Amphioxus, as the closest living invertebrate relative of the vertebrates, can give insights
into the evolutionary origin of the vertebrate body plan. Therefore, to investigate the …

EMX2 and PAX6 are expressed by cortical progenitors and specify area patterning. We used
representational difference analysis (RDA) to compare expressed RNAs from wild type and …