Monoclonal antibodies are a growing class of targeted cancer therapeutics, characterized by
exquisite specificity, long serum half-life, high affinity and immune effector functions. In this …

The prevalence of allergies has been globally escalating. While allergies could appear at
any age, they often develop in early life. However, the significant knowledge gap in the field …

Binding to the neonatal Fc receptor (FcRn) extends serum half-life of IgG, and antagonizing
this interaction is a promising therapeutic approach in IgG-mediated autoimmune diseases …

Abs can be glycosylated in both their Fc and Fab regions with marked effects on Ab function
and binding. High levels of IgG Fab glycosylation are associated with malignant and …

Feto-maternal microchimerism is the bidirectional transfer of cells through the placenta
during pregnancy that can affect the health of both the mother and the offspring, even in …