Dexmedetomidin is a new-generation, highly selective α2 adrenergic receptor agonist with a
large number of advantages, including its sedative and analgesic properties, its ability to …

Dexmedetomidine (DEX) is a highly selective α2 receptor agonist that is routinely used in
the clinic for sedation and anesthesia. Recently, an increasing number of studies have …

Neuroinflammation is critical in the pathogenesis of neurological diseases. Microglial pro-
inflammatory (M1) and anti-inflammatory (M2) status determines the outcome of …

Dexmedetomidine (DEX) is a highly selective α2-adrenergic agonist with sedative and
analgesic properties, with minimal respiratory effects. It is used as a sedative in the intensive …

Dexmedetomidine (Dex) has the neuroprotective effect on cerebral ischemia-reperfusion
injury (CIRI). But the mechanism is not yet clear. In this study, we established a model of …

Numerous studies have indicated the pharmacological properties of linalool, a volatile
terpene alcohol found in many flowers and spice plants, including anti‐nociceptive, anti …

Background: Postoperative cognitive dysfunction (POCD) is associated with prolonged
hospital stays, increased mortality, and negative socioeconomic consequences …

Prolonged abuse of methylphenidate (MPH) often causes neuronal damage. Topiramate
(TPM) has neuroprotective properties, but its mechanism of action remains unclear. The …

Study Design. To evaluate the effect of Dexmedetomidine (Dex) on the inflammatory
response and the integrity of blood–spinal cord barrier (BSCB) after spinal cord ischemia …

Dexmedetomidine (Dex) possesses analgesic and anaesthetic values and reported being
used in cerebral ischaemic injury therapeutics. Accumulating studies have determined the …