MicroRNAs in animal models of HCC

F Fornari, L Gramantieri, E Callegari, RC Shankaraiah… - Cancers, 2019 - mdpi.com
Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related mortality.
Molecular heterogeneity and absence of biomarkers for patient allocation to the best …

Targeting non-coding RNAs and N6-methyladenosine modification in hepatocellular carcinoma

L Wu, Y Zhang, J Ren - Biochemical Pharmacology, 2024 - Elsevier
Hepatocellular carcinoma (HCC), the most common form of primary liver cancers, accounts
for a significant portion of cancer-related death globally. However, the molecular …

Oncogene-dependent function of BRG1 in hepatocarcinogenesis

P Wang, X Song, D Cao, K Cui, J Wang, K Utpatel… - Cell death & …, 2020 - nature.com
Hepatocellular carcinoma (HCC) is the major type of primary liver cancer. Genomic studies
have revealed that HCC is a heterogeneous disease with multiple subtypes. BRG1 …

The target microRNAs and potential underlying mechanisms of Yiqi-Bushen-Tiaozhi recipe against‐non-alcoholic steatohepatitis

W Hong, S Li, Y Cai, T Zhang, Q Yang, B He… - Frontiers in …, 2020 - frontiersin.org
MicroRNAs (miRNAs) have emerged as potential therapeutic targets for non-alcoholic fatty
liver disease/non-alcoholic steatohepatitis (NAFLD/NASH). Traditional Chineses Medicine …

Biology and clinical application of regulatory RNAs in hepatocellular carcinoma

A Pea, NB Jamieson, C Braconi - Hepatology, 2021 - Wiley Online Library
Most of the human genome consists of DNA genes that are translated into RNAs but not into
proteins. These RNA molecules are named noncoding RNAs (ncRNA). While in the past it …

Biliary tract cancer: molecular biology of precursor lesions

F Manzano-Núñez, LPT Aguilar… - Seminars in liver …, 2023 - thieme-connect.com
Biliary tract cancer is a devastating malignancy of the bile ducts and gallbladder with a
dismal prognosis. The study of precancerous lesions has received considerable attention …

[HTML][HTML] The Wnt signaling pathway in hepatocellular carcinoma: Regulatory mechanisms and therapeutic prospects

S Ma, G Meng, T Liu, J You, R He, X Zhao… - Biomedicine & …, 2024 - Elsevier
Hepatocellular carcinoma (HCC) is a malignant tumor that arises from hepatocytes. Multiple
signaling pathways play a regulatory role in the occurrence and development of HCC, with …

A minimal subset of seven genes associated with tumor hepatocyte differentiation predicts a poor prognosis in human hepatocellular carcinoma

M Desoteux, C Louis, K Bévant, D Glaise, C Coulouarn - Cancers, 2021 - mdpi.com
Simple Summary Liver cancer is one of the most commonly diagnosed cancers worldwide
and the fourth leading cause of cancer-related deaths. Hepatocellular carcinoma (HCC) …

[HTML][HTML] Identification of novel targets of miR-622 in hepatocellular carcinoma reveals common regulation of cooperating genes and outlines the oncogenic role of zinc …

A Gaza, V Fritz, L Malek, L Wormser, N Treiber… - Neoplasia, 2021 - Elsevier
The poor prognosis of advanced hepatocellular carcinoma (HCC) is driven by diverse
features including dysregulated microRNAs inducing drug resistance and stemness. Lin-28 …

In silico Prediction on the PI3K/AKT/mTOR Pathway of the Antiproliferative Effect of O. joconostle in Breast Cancer Models

A Ortiz-González, PP González-Pérez… - Cancer …, 2022 - journals.sagepub.com
The search for new cancer treatments from traditional medicine involves developing studies
to understand at the molecular level different cell signaling pathways involved in cancer …