The regulation of telomere length in mammals is crucial for chromosome end-capping and
thus for maintaining genome stability and cellular lifespan. This process requires …

Telomeres are DNA-protein complexes that cap and protect the ends of linear
chromosomes. In almost all species, telomeric DNA has a G/C strand bias, and the short …

Telomerase adds telomeric repeats at chromosome ends to compensate for the telomere
loss that is caused by incomplete genome end replication. In humans, telomerase is …

Telomerase is a special reverse transcriptase ribonucleoprotein dedicated to the synthesis
of telomere repeats that protect chromosome ends. Among reverse transcriptases …

Electromagnetic forces and torques enable many key technologies, including optical
tweezers or dielectrophoresis. Interestingly, both techniques rely on the same physical …

Telomerase is unique among the reverse transcriptases in containing a noncoding RNA
(known as telomerase RNA (TER)) that includes a short template that is used for the …

G-quadruplexes (G4s) are peculiar nucleic acid secondary structures formed by DNA or
RNA and are considered as fundamental features of the genome. Many proteins can …

Telomerase is an RNA–protein complex comprising telomerase reverse transcriptase, a non-
coding telomerase RNA, and proteins involved in biogenesis, assembly, localization, or …

Telomeric G-quadruplexes (G4) were long believed to form a protective structure at
telomeres, preventing their extension by the ribonucleoprotein telomerase. Contrary to this …

Telomerase is a specialized reverse transcriptase that adds GGTTAG repeats to
chromosome ends and is upregulated in most human cancers to enable limitless …