[HTML][HTML] Recent advances in high-throughput biofluid metabotyping by direct infusion and ambient ionization mass spectrometry

V Plekhova, K De Windt, M De Spiegeleer… - TrAC Trends in …, 2023 - Elsevier
Biofluid metabolomics is a popular tool for biomarker discovery to decipher disease-,
genetics-, and exposure-related metabolic alterations and is an essential component for …

Recent Contributions of Mass Spectrometry-Based “Omics” in the Studies of Breast Cancer

S Banerjee, M Hatimuria, K Sarkar, J Das… - Chemical Research …, 2023 - ACS Publications
Breast cancer (BC) is one of the most heterogeneous groups of cancer. As every biotype of
BC is unique and presents a particular “omic” signature, they are increasingly characterized …

Metabolic-dysregulation-based iEESI-MS reveals potential biomarkers associated with early-stage and progressive colorectal cancer

R Zheng, R Su, F Xing, Q Li, B Liu, D Wang… - Analytical …, 2022 - ACS Publications
The application of rapid and accurate diagnostic methods can improve colorectal cancer
(CRC) survival rates dramatically. Here, we used a non-targeted metabolic analysis strategy …

[HTML][HTML] Kidney and plasma metabolomics provide insights into the molecular mechanisms of urate nephropathy in a mouse model of hyperuricemia

H Li, H Zhang, F Yan, Y He, A Ji, Z Liu, M Li, X Ji… - Biochimica et Biophysica …, 2022 - Elsevier
Hyperuricemia (HUA) is closely associated with kidney damage and kidney diseases in
humans; however, the underlying mechanisms of HUA-induced kidney diseases remain …

Screening and diagnosis of triple negative breast cancer based on rapid metabolic fingerprinting by conductive polymer spray ionization mass spectrometry and …

Y Song, Y Zhang, S Xie, X Song - Frontiers in Cell and …, 2022 - frontiersin.org
We present the use of conductive spray polymer ionization mass spectrometry (CPSI-MS)
combined with machine learning (ML) to rapidly gain the metabolic fingerprint from 1 μl …

Introducing Nafion for In Situ Desalting and Biofluid Profiling in Spray Mass Spectrometry

X Song, M Mofidfar, RN Zare - Frontiers in Chemistry, 2022 - frontiersin.org
We introduce Nafion into the ambient ionization technique of spray mass spectrometry to
serve for in situ desalting and direct analysis of biological fluids. Nafion was coated onto the …

Distinguishing between isobaric ions using microdroplet hydrogen–deuterium exchange mass spectrometry

X Song, J Li, M Mofidfar, RN Zare - Metabolites, 2021 - mdpi.com
Isobaric ions having the same mass-to-charge ratio cannot be separately identified by mass
spectrometry (MS) alone, but this limitation can be overcome by using hydrogen–deuterium …

The metabolomics research progress of exploring biomarkers for colorectal cancer

W Hua-guang, L Jiang, Z Ying, D Xian… - Chinese Journal of …, 2024 - ywfx.nifdc.org.cn
Metabolomics, as a branch of systems biology, utilizes high-throughput omics technology to
investigate metabolite changes within organisms, which enable us to explore the …