Mono-and sesquiterpenes as a starting platform for the development of antiviral drugs

OI Yarovaya, NF Salakhutdinov - Russian Chemical Reviews, 2021 - iopscience.iop.org
The revies focuses on low-molecular-weight plant metabolites (mono-and sesquiterpenes)
exhibiting antiviral activity. Data on antiviral action of both essential oils and plant extracts …

Recent progress in chemical approaches for the development of novel neuraminidase inhibitors

A Mahal, M Duan, DS Zinad, RK Mohapatra… - RSC …, 2021 - pubs.rsc.org
Influenza virus is the main cause of an infectious disease called influenza affecting the
respiratory system including the throat, nose and lungs. Neuraminidase inhibitors are …

Discovery of multitarget-directed ligands against influenza a virus from compound yizhihao through a predictive system for compound-protein interactions

L Xu, W Jiang, H Jia, L Zheng, J Xing, A Liu… - Frontiers in cellular and …, 2020 - frontiersin.org
Influenza A virus (IAV) is a threat to public health due to its high mutation rate and resistance
to existing drugs. In this investigation, 15 targets selected from an influenza virus–host …

An Estimation of the Antiviral Activity and Toxicity of Biologically Active Substances Obtained from the Raw Materials of Artemisia cina Berg. In Vitro and In Vivo

M Zhurinov, D Berillo, KB Bazhykova, KD Rakhimov… - Molecules, 2023 - mdpi.com
Species of the genus Artemisia are well known for their use as ingredients in ancient
medicine. The advantage of using plant extracts compared to individual pharmaceutical …

Metabolomic profiling of Sansevieria trifasciata hort ex. Prain leaves and roots by HPLC-PAD-ESI/MS and its hepatoprotective effect via activation of the NRF2/ARE …

M Raslan, R Abdel Rahman, H Fayed… - Egyptian Journal of …, 2021 - ejchem.journals.ekb.eg
Sansevieria species show various bioactivities. Nevertheless, its therapeutic prospect in
liver fibrosis even now is uninvestigated. The present study was conducted to analyze the …

[HTML][HTML] Моно-и сесквитерпены в качестве стартовой платформы для создания противовирусных средств

ОИ Яровая, НФ Салахутдинов - Успехи химии, 2021 - uspkhim.ru
Аннотация Обзор посвящен низкомолекулярным растительным метаболитам моно-и
сесквитерпенового рядов, которые проявляют противовирусную активность …

Sesquiterpenes and Sesquiterpene Derivatives from Ferula: Their Chemical Structures, Biosynthetic Pathways, and Biological Properties

J Wang, Q Zheng, H Wang, L Shi, G Wang, Y Zhao… - Antioxidants, 2023 - mdpi.com
Ferula is a genus of flowering plants known for its edible and medicinal properties. Since
ancient times, many species of Ferula have been used in traditional medicine to treat …

Isolation and evaluation of antiviral plant compounds against respiratory disease-causing viruses: a review

TR Mahendran, B Cynthia, G Manickavasagam… - Advances in Traditional …, 2024 - Springer
Influenza viruses are major concern worldwide due to their fast ability to spread, and
causing the respiratory illness of varying severity. The rate of travel, urbanization and …

Synthesis and Antiviral Activity of New Derivatives of Rupestonic Acid

L Chen, M Obul, K Bozorov, J Zhao - Chemistry of Natural Compounds, 2021 - Springer
A series of 20 new derivatives of rupestonic acid were synthesized via Davis oxidation. Their
antiviral activity against influenza A virus (H3N2) was established. Several of the …

Synthesis and Cytotoxic Activity of a New Derivative of Rupestonic Acid

P Aibibula, HA Aisa, K Bozorov, J Zhao - Chemistry of Natural Compounds, 2023 - Springer
Twenty new amide derivatives of rupestonic acid were synthesized. Their cytotoxic activities
against four human cancer cell lines (HeLa, HT-29, A549, and HepG2) were established …