Chronic liver diseases are frequent and potentially life threatening for humans. The
underlying etiologies are diverse, ranging from viral infections, autoimmune disorders, and …

Schistosomiasis, caused by human trematode blood flukes (schistosomes), remains one of
the most prevalent and serious of the neglected tropical parasitic diseases. Currently …

Despite intensive long-term efforts, with very few exceptions, the development of effective
vaccines against parasitic infections has presented considerable challenges, given the …

Background Praziquantel (PZQ) is an isoquinoline derivative (2-cyclohexylcarbonyl-1, 2, 3,
6, 7, 11b-hexahydro-4H-pyrazino {2, 1-a}-isoquinoline-4-one), and is currently the drug of …

Background. Schistosome infections are often clinically silent, but some individuals develop
severe pathological reactions. In several disease processes, T-helper 17 (Th17) cells have …

S chistosomiasis japonica is a severe tropical disease caused by the parasitic worm S
chistosoma japonicum. Among the most serious pathological effects of S. japonicum …

Schistosomiasis is a disease of global significance, with severity and pathology directly
related to how the host responds to infection. The immunological narrative of …

Background The current knowledge of immunological responses to schistosomiasis, a major
tropical helminthic disease, is insufficient, and a better understanding of these responses …

Background Schistosomiasis is a parasitic disease infecting more than 200 million people in
the world. Although chemotherapy targeting on killing schistosomes is one of the main …

The pathology of schistosomiasis mansoni, a neglected tropical disease of great clinical and
socioeconomic importance, results from the parasite eggs that become trapped in host …