Dermal substitutes provide a template for dermal regeneration and reconstruction. They
constitutes an ideal clinical treatment for deep skin defects. However, rapid vascularization …

An extensive network of cutaneous nerves, neuropeptides, and specific receptors richly
innervates the skin and influences a variety of physiological and pathological processes …

Nanotechnology applications in biomedicine have increased in recent decades, primarily as
therapeutic agents, drugs, and gene delivery systems. Among the nanoparticles used in …

Impaired cutaneous healing leading to chronic wounds affects between 2 and 6% of the total
population in most developed countries and it places a substantial burden on healthcare …

The construction of efficient and low toxic non-viral gene delivery vectors is of great
significance for gene therapy. Herein, two novel polycations were constructed via Michael …

The good treatment of skin defects has always been a challenge in the medical field, and the
emergence of tissue engineering skin provides a new idea for the treatment of injured skin …

Successful clinical implementation of gene delivery relies on the use of viral or non‐viral
based vectors to package and protect the therapeutic nucleic acid. These vehicles must also …

The safe and efficient delivery of nucleic acids is crucial for both clinical applications of gene
therapy and pre-clinical laboratory research. Such delivery strategies rely on vectors to …

We evaluated the expression profiles of differentially expressed miRNAs (DEmiRNAs)
involved in human fetal skin development via high-throughput sequencing to explore the …

Healing of cutaneous wounds is a multi-cellular and multi-molecular process which occurs
after loss of skin integrity involving a complex signaling network, cells interactions and …