Vascularization and angiogenesis in tissue engineering: beyond creating static networks

J Rouwkema, A Khademhosseini - Trends in biotechnology, 2016 - cell.com
Engineered tissues need a vascular network to supply cells with nutrients and oxygen after
implantation. A network that can connect to the vasculature of the patient after implantation …

3D bioprinting for cartilage and osteochondral tissue engineering

AC Daly, FE Freeman… - Advanced …, 2017 - Wiley Online Library
Significant progress has been made in the field of cartilage and bone tissue engineering
over the last two decades. As a result, there is real promise that strategies to regenerate …

3D bioprinting spatiotemporally defined patterns of growth factors to tightly control tissue regeneration

FE Freeman, P Pitacco, LHA van Dommelen… - Science …, 2020 - science.org
Therapeutic growth factor delivery typically requires supraphysiological dosages, which can
cause undesirable off-target effects. The aim of this study was to 3D bioprint implants …

Porous biomaterials for tissue engineering: a review

FJ Maksoud, MFV de la Paz, AJ Hann… - Journal of Materials …, 2022 - pubs.rsc.org
The field of biomaterials has grown rapidly over the past decades. Within this field, porous
biomaterials have played a remarkable role in:(i) enabling the manufacture of complex three …

Designing of gradient scaffolds and their applications in tissue regeneration

A Pattnaik, AS Sanket, S Pradhan, R Sahoo, S Das… - Biomaterials, 2023 - Elsevier
Gradient scaffolds are isotropic/anisotropic three-dimensional structures with gradual
transitions in geometry, density, porosity, stiffness, etc., that mimic the biological extracellular …

Strategies to promote vascularization in 3D printed tissue scaffolds: trends and challenges

A Joshi, S Choudhury, SB Gugulothu… - …, 2022 - ACS Publications
Three-dimensional (3D) printing techniques for scaffold fabrication have shown promising
advancements in recent years owing to the ability of the latest high-performance printers to …

Design and fabrication of complex scaffolds for bone defect healing: combined 3D plotting of a calcium phosphate cement and a growth factor-loaded hydrogel

T Ahlfeld, AR Akkineni, Y Förster, T Köhler… - Annals of biomedical …, 2017 - Springer
Additive manufacturing enables the fabrication of scaffolds with defined architecture.
Versatile printing technologies such as extrusion-based 3D plotting allow in addition the …

RGD nanoarrays with nanospacing gradient selectively induce orientation and directed migration of endothelial and smooth muscle cells

J He, R Shen, Q Liu, S Zheng, X Wang… - … Applied Materials & …, 2022 - ACS Publications
Directed migration of cells through cell–surface interactions is a paramount prerequisite in
biomaterial-induced tissue regeneration. However, whether and how the nanoscale spatial …

Collagen type I: A versatile biomaterial

SR Chowdhury, MF Mh Busra, Y Lokanathan… - Novel biomaterials for …, 2018 - Springer
Collagen type I is the most abundant matrix protein in the human body and is highly
demanded in tissue engineering, regenerative medicine, and pharmaceutical applications …

Novel advances in the design of three-dimensional bio-scaffolds to control cell fate: translation from 2D to 3D

E Santos, RM Hernández, JL Pedraz, G Orive - Trends in biotechnology, 2012 - cell.com
Recreating the most critical aspects of the native extracellular matrix (ECM) is fundamental
to understand and control the processes regulating cell fate and cell function. From the ill …